Mycobacterium tuberculosis Rv0928 protein facilitates macrophage control of mycobacterium infection by promoting mitochondrial intrinsic apoptosis and ROS-mediated inflammation

Mycobacterium tuberculosis Rv0928 protein facilitates macrophage control of mycobacterium infection by promoting mitochondrial intrinsic apoptosis and ROS-mediated inflammation

Macrophages are the main target cells for Mycobacterium tuberculosis (Mtb) infection. Previous studies have shown that Mtb actively upregulates phosphorus transport proteins, such as Rv0928 protein (also known as PstS3), to increase inorganic phosphate uptake and promote their survival under low pho...

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Bibliographic Details
Main Authors: Chenling Xu, Yan Yue, Sidong Xiong
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Microbiology
Subjects:
Mycobacterium tuberculosis
Rv0928
SLC25A3
mitochondrion
apoptosis
inflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2023.1291358/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2023.1291358/full

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