Potent immunity to low doses of influenza vaccine by probabilistic guided micro-targeted skin delivery in a mouse model.

Potent immunity to low doses of influenza vaccine by probabilistic guided micro-targeted skin delivery in a mouse model.

<h4>Background</h4>Over 14 million people die each year from infectious diseases despite extensive vaccine use [1]. The needle and syringe--first invented in 1853--is still the primary delivery device, injecting liquid vaccine into muscle. Vaccines could be far more effective if they wer...

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Bibliographic Details
Main Authors: Germain J P Fernando, Xianfeng Chen, Tarl W Prow, Michael L Crichton, Emily J Fairmaid, Michael S Roberts, Ian H Frazer, Lorena E Brown, Mark A F Kendall
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-04-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20422002/pdf/?tool=EBI

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