Assessment of minerals in biological fluids in people with obesity: A pilot study
Background and Aim: Obesity is a multifactorial disease that can lead to nutritional metabolic disorders, in which the general state of trace elements and minerals are altered. Thus, research involving biological fluids to assess the metabolic nutritional status of minerals Manganese (Mn); Selenium...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-03-01
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| Series: | Journal of Trace Elements and Minerals |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2773050623000071 |
| _version_ | 1811166118628294656 |
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| author | Gizela Pedroso Junqueira Márcia Varella Morandi Junqueira-Franco Rocio San Martin Camila Fernanda Cunha Brandão Fernando Barbosa Júnior Eduardo Melani Rocha Fernando Bahdur Chueire Julio Sergio Marchini |
| author_facet | Gizela Pedroso Junqueira Márcia Varella Morandi Junqueira-Franco Rocio San Martin Camila Fernanda Cunha Brandão Fernando Barbosa Júnior Eduardo Melani Rocha Fernando Bahdur Chueire Julio Sergio Marchini |
| author_sort | Gizela Pedroso Junqueira |
| collection | DOAJ |
| description | Background and Aim: Obesity is a multifactorial disease that can lead to nutritional metabolic disorders, in which the general state of trace elements and minerals are altered. Thus, research involving biological fluids to assess the metabolic nutritional status of minerals Manganese (Mn); Selenium (Se); Strontium (Sr); Zinc (Zn); Molybdenum (Mo); Copper (Cu); Iron (Fe); Calcium (Ca); Magnesium (Mg) and Chromium (Cr) are essential in people with obesity. Therefore, the aim of this study was to evaluate the concentrations of these trace elements and minerals in different biological fluids (plasma, erythrocytes, saliva, urine and tear) from people with and without obesity. Methods: The experimental sample consisted of 28 volunteers divided into two groups: Obesity Group (OG, n = 14) and Non-Obese (NO, n = 14), who were clinically evaluated by anthropometry, body composition and biochemical tests. Minerals were assessed in different biological fluids (plasma, erythrocyte, saliva, urine and tear) using the ICP-MS methodology. A significance level of 5% (p < 0.05) was considered. Data were shown as mean ± standard deviation. Results: Anthropometric evaluation, body composition and LDL-cholesterol were significantly higher in the OG (p < 0.05), as expected. Plasma minerals were significantly lower in OG than the NO (Se = 184±102 vs 229±83 µg/L (p= = 0.027); Fe= 578±346 vs 1099±529 µg/L (p = 0.005), respectively). Erythrocyte and salivary minerals were significantly higher in, in OG than the NO, (erythrocyte Mg = 5.8 ± 0.8 vs 5.0 ± 0.7 mg/dL (p = 0.041) and salivary Ca = 2.7 ± 0.9 vs 1.8 ± 1.0 mg/dL (p = 0.027), respectively). Furthermore, urine minerals were significantly lower in OG than the NO, (Se = 17.4 ± 5.6 vs 26.0 ± 12.7 µg/L (p = 0.034) and Mo = 27.0 ± 14.3 vs 52±39.2 µg/L (p = 0.041), respectively). Regarding tears, there was no difference between groups (p > 0.05). Conclusion: Our study provides a better understanding of minerals concentrations in different biological fluids in people with obesity. Besides, this study may contribute to future identification of potential minerals biomarkers. However, considering our study's major limitation was its small sample size, caution should be taken when interpreting the results. |
| first_indexed | 2024-04-10T15:47:21Z |
| format | Article |
| id | doaj.art-5141b46f124b44ddb748d8d3c11ae5c3 |
| institution | Directory Open Access Journal |
| issn | 2773-0506 |
| language | English |
| last_indexed | 2024-04-10T15:47:21Z |
| publishDate | 2023-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Trace Elements and Minerals |
| spelling | doaj.art-5141b46f124b44ddb748d8d3c11ae5c32023-02-12T04:15:57ZengElsevierJournal of Trace Elements and Minerals2773-05062023-03-013100052Assessment of minerals in biological fluids in people with obesity: A pilot studyGizela Pedroso Junqueira0Márcia Varella Morandi Junqueira-Franco1Rocio San Martin2Camila Fernanda Cunha Brandão3Fernando Barbosa Júnior4Eduardo Melani Rocha5Fernando Bahdur Chueire6Julio Sergio Marchini7Department of Health Sciences, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil; Department of Internal Medicine, Division of Nutrology, Ribeirão Preto Medical School - University of São Paulo, Ribeirão Preto, São Paulo, Brazil; Corresponding author at: Ribeirão Preto Medical School - FMRP/USP Av. Bandeirantes, 3900. – Monte Alegre - Ribeirão Preto, SP/Brazil 14049-900.Department of Internal Medicine, Division of Nutrology, Ribeirão Preto Medical School - University of São Paulo, Ribeirão Preto, São Paulo, BrazilDepartment of Internal Medicine, Division of Nutrology, Ribeirão Preto Medical School - University of São Paulo, Ribeirão Preto, São Paulo, BrazilDepartment of Internal Medicine, Division of Nutrology, Ribeirão Preto Medical School - University of São Paulo, Ribeirão Preto, São Paulo, Brazil; Department of Phisical Education at the University State of Minas Gerais, Divinópolis, Minas Gerais, BrazilAnalytical and System Toxicology Laboratory, Department of Clinical Analyses, Toxicology and Food Sciences, School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, Ribeirão Preto, São Paulo, BrazilDepartment of Ophthalmology, Otorhinolaryngology and Head and Neck Surgery, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, BrazilDepartment of Internal Medicine, Division of Nutrology, Ribeirão Preto Medical School - University of São Paulo, Ribeirão Preto, São Paulo, BrazilDepartment of Health Sciences, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil; Department of Internal Medicine, Division of Nutrology, Ribeirão Preto Medical School - University of São Paulo, Ribeirão Preto, São Paulo, BrazilBackground and Aim: Obesity is a multifactorial disease that can lead to nutritional metabolic disorders, in which the general state of trace elements and minerals are altered. Thus, research involving biological fluids to assess the metabolic nutritional status of minerals Manganese (Mn); Selenium (Se); Strontium (Sr); Zinc (Zn); Molybdenum (Mo); Copper (Cu); Iron (Fe); Calcium (Ca); Magnesium (Mg) and Chromium (Cr) are essential in people with obesity. Therefore, the aim of this study was to evaluate the concentrations of these trace elements and minerals in different biological fluids (plasma, erythrocytes, saliva, urine and tear) from people with and without obesity. Methods: The experimental sample consisted of 28 volunteers divided into two groups: Obesity Group (OG, n = 14) and Non-Obese (NO, n = 14), who were clinically evaluated by anthropometry, body composition and biochemical tests. Minerals were assessed in different biological fluids (plasma, erythrocyte, saliva, urine and tear) using the ICP-MS methodology. A significance level of 5% (p < 0.05) was considered. Data were shown as mean ± standard deviation. Results: Anthropometric evaluation, body composition and LDL-cholesterol were significantly higher in the OG (p < 0.05), as expected. Plasma minerals were significantly lower in OG than the NO (Se = 184±102 vs 229±83 µg/L (p= = 0.027); Fe= 578±346 vs 1099±529 µg/L (p = 0.005), respectively). Erythrocyte and salivary minerals were significantly higher in, in OG than the NO, (erythrocyte Mg = 5.8 ± 0.8 vs 5.0 ± 0.7 mg/dL (p = 0.041) and salivary Ca = 2.7 ± 0.9 vs 1.8 ± 1.0 mg/dL (p = 0.027), respectively). Furthermore, urine minerals were significantly lower in OG than the NO, (Se = 17.4 ± 5.6 vs 26.0 ± 12.7 µg/L (p = 0.034) and Mo = 27.0 ± 14.3 vs 52±39.2 µg/L (p = 0.041), respectively). Regarding tears, there was no difference between groups (p > 0.05). Conclusion: Our study provides a better understanding of minerals concentrations in different biological fluids in people with obesity. Besides, this study may contribute to future identification of potential minerals biomarkers. However, considering our study's major limitation was its small sample size, caution should be taken when interpreting the results.http://www.sciencedirect.com/science/article/pii/S2773050623000071Trace elementsObesityBiomarkersNutritionMinerals |
| spellingShingle | Gizela Pedroso Junqueira Márcia Varella Morandi Junqueira-Franco Rocio San Martin Camila Fernanda Cunha Brandão Fernando Barbosa Júnior Eduardo Melani Rocha Fernando Bahdur Chueire Julio Sergio Marchini Assessment of minerals in biological fluids in people with obesity: A pilot study Journal of Trace Elements and Minerals Trace elements Obesity Biomarkers Nutrition Minerals |
| title | Assessment of minerals in biological fluids in people with obesity: A pilot study |
| title_full | Assessment of minerals in biological fluids in people with obesity: A pilot study |
| title_fullStr | Assessment of minerals in biological fluids in people with obesity: A pilot study |
| title_full_unstemmed | Assessment of minerals in biological fluids in people with obesity: A pilot study |
| title_short | Assessment of minerals in biological fluids in people with obesity: A pilot study |
| title_sort | assessment of minerals in biological fluids in people with obesity a pilot study |
| topic | Trace elements Obesity Biomarkers Nutrition Minerals |
| url | http://www.sciencedirect.com/science/article/pii/S2773050623000071 |
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