Repurposing EGFR Inhibitors for Oral Cancer Pain and Opioid Tolerance

Repurposing EGFR Inhibitors for Oral Cancer Pain and Opioid Tolerance

Oral cancer pain remains a significant public health concern. Despite the development of improved treatments, pain continues to be a debilitating clinical feature of the disease, leading to reduced oral mobility and diminished quality of life. Opioids are the gold standard treatment for moderate-to-...

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Bibliographic Details
Main Authors: Maria Daniela Santi, Morgan Zhang, Naijiang Liu, Chi T. Viet, Tongxin Xie, Dane D. Jensen, Moran Amit, Huilin Pan, Yi Ye
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Pharmaceuticals
Subjects:
oral cancer pain
EGFR
morphine tolerance
µ-opioid receptor
NMDA receptor
Online Access:https://www.mdpi.com/1424-8247/16/11/1558

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