A comprehensive comparison between camelid nanobodies and single chain variable fragments

A comprehensive comparison between camelid nanobodies and single chain variable fragments

Abstract By the emergence of recombinant DNA technology, many antibody fragments have been developed devoid of undesired properties of natural immunoglobulins. Among them, camelid heavy-chain variable domains (VHHs) and single-chain variable fragments (scFvs) are the most favored ones. While scFv is...

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Bibliographic Details
Main Authors: Yasaman Asaadi, Fatemeh Fazlollahi Jouneghani, Sara Janani, Fatemeh Rahbarizadeh
Format: Article
Language:English
Published: BMC 2021-12-01
Series:Biomarker Research
Subjects:
Single-chain variable fragment (scFv)
camelid VHH
nanobody
single-domain antibody
Online Access:https://doi.org/10.1186/s40364-021-00332-6

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