Enhancing the dissolution rate of poorly soluble drug Febuxostat using spray dried amorphous solid dispersion technique

Enhancing the dissolution rate of poorly soluble drug Febuxostat using spray dried amorphous solid dispersion technique

Abstract Introduction: Febuxostat belongs to Biopharmaceutical classification system (BCS) class II drugs, which have low solubility and high permeability. Amorphous solid dispersion is one of the techniques which can be useful to improve solubility and powder characteristics. Objective: To optimi...

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Bibliographic Details
Main Authors: Vaishali Patel, Anita Patel, Ashish Shah
Format: Article
Language:English
Published: Facultad de Farmacia, Universidad de Granada 2023-06-01
Series:Ars Pharmaceutica
Subjects:
Febuxostat
Amorphous Solid dispersion
Kollidon SR
HPMC K4M
Full factorial design
Online Access:http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S2340-98942023000200004&tlng=en

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