Case report: Successful experience using continuous infusion of meropenem in a geriatric patient with hip fracture complicated by sepsis

This article highlights a clinical case of successful treatment of a 79-year-old multimorbid patient with a hip fracture resulting from a household injury. On the first day, the patient’s injury was complicated by infection and pneumonia. As a result, arterial hypotension, tachysystole, and respirat...

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Main Authors: Assiya Kadralinova, Assema Zh. Bekniyazova, Maiya E. Konkayeva, Aigerim A. Yeltayeva, Aidos K. Konkayev
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Medicine
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2023.1148555/full
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author Assiya Kadralinova
Assema Zh. Bekniyazova
Assema Zh. Bekniyazova
Maiya E. Konkayeva
Aigerim A. Yeltayeva
Aigerim A. Yeltayeva
Aidos K. Konkayev
Aidos K. Konkayev
author_facet Assiya Kadralinova
Assema Zh. Bekniyazova
Assema Zh. Bekniyazova
Maiya E. Konkayeva
Aigerim A. Yeltayeva
Aigerim A. Yeltayeva
Aidos K. Konkayev
Aidos K. Konkayev
author_sort Assiya Kadralinova
collection DOAJ
description This article highlights a clinical case of successful treatment of a 79-year-old multimorbid patient with a hip fracture resulting from a household injury. On the first day, the patient’s injury was complicated by infection and pneumonia. As a result, arterial hypotension, tachysystole, and respiratory failure progressed. With manifestations of sepsis, the patient was transferred to the intensive care unit. Surgical treatment in such a situation was contraindicated due to the high operational and anesthesiological risks, the unstable severe condition of the patient, as well as the presence of concomitant pathology in the form of coronary heart disease, obesity, and schizophrenia. According to the new sepsis management guideline, it was decided to use a continuous 24-h infusion of meropenem in addition to the complex treatment of sepsis. The use of continuous infusion of meropenem in this clinical situation may have caused the patient’s clinical improvement, which increased her quality of life and decreased the length of ICU stay and total hospital stay, despite an unfavorable cumulative prognosis and a high risk of in-hospital mortality.
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spelling doaj.art-51467d3f3f6743abab11480f7e81de5b2023-04-27T05:29:00ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2023-04-011010.3389/fmed.2023.11485551148555Case report: Successful experience using continuous infusion of meropenem in a geriatric patient with hip fracture complicated by sepsisAssiya Kadralinova0Assema Zh. Bekniyazova1Assema Zh. Bekniyazova2Maiya E. Konkayeva3Aigerim A. Yeltayeva4Aigerim A. Yeltayeva5Aidos K. Konkayev6Aidos K. Konkayev7Department of Anesthesiology and Intensive Care, Astana Medical University, Astana, KazakhstanDepartment of Anesthesiology and Intensive Care, Astana Medical University, Astana, KazakhstanDepartment of Anesthesiology and Intensive Care, National Scientific Center of Traumatology and Orthopedics named after Academician N.D. Batpenov, Astana, KazakhstanDepartment of Anesthesiology and Intensive Care, Astana Medical University, Astana, KazakhstanDepartment of Anesthesiology and Intensive Care, Astana Medical University, Astana, KazakhstanDepartment of Anesthesiology and Intensive Care, National Scientific Center of Traumatology and Orthopedics named after Academician N.D. Batpenov, Astana, KazakhstanDepartment of Anesthesiology and Intensive Care, Astana Medical University, Astana, KazakhstanDepartment of Anesthesiology and Intensive Care, National Scientific Center of Traumatology and Orthopedics named after Academician N.D. Batpenov, Astana, KazakhstanThis article highlights a clinical case of successful treatment of a 79-year-old multimorbid patient with a hip fracture resulting from a household injury. On the first day, the patient’s injury was complicated by infection and pneumonia. As a result, arterial hypotension, tachysystole, and respiratory failure progressed. With manifestations of sepsis, the patient was transferred to the intensive care unit. Surgical treatment in such a situation was contraindicated due to the high operational and anesthesiological risks, the unstable severe condition of the patient, as well as the presence of concomitant pathology in the form of coronary heart disease, obesity, and schizophrenia. According to the new sepsis management guideline, it was decided to use a continuous 24-h infusion of meropenem in addition to the complex treatment of sepsis. The use of continuous infusion of meropenem in this clinical situation may have caused the patient’s clinical improvement, which increased her quality of life and decreased the length of ICU stay and total hospital stay, despite an unfavorable cumulative prognosis and a high risk of in-hospital mortality.https://www.frontiersin.org/articles/10.3389/fmed.2023.1148555/fullhip fracturesepsispneumoniacontinuous infusionmeropenemcase report
spellingShingle Assiya Kadralinova
Assema Zh. Bekniyazova
Assema Zh. Bekniyazova
Maiya E. Konkayeva
Aigerim A. Yeltayeva
Aigerim A. Yeltayeva
Aidos K. Konkayev
Aidos K. Konkayev
Case report: Successful experience using continuous infusion of meropenem in a geriatric patient with hip fracture complicated by sepsis
Frontiers in Medicine
hip fracture
sepsis
pneumonia
continuous infusion
meropenem
case report
title Case report: Successful experience using continuous infusion of meropenem in a geriatric patient with hip fracture complicated by sepsis
title_full Case report: Successful experience using continuous infusion of meropenem in a geriatric patient with hip fracture complicated by sepsis
title_fullStr Case report: Successful experience using continuous infusion of meropenem in a geriatric patient with hip fracture complicated by sepsis
title_full_unstemmed Case report: Successful experience using continuous infusion of meropenem in a geriatric patient with hip fracture complicated by sepsis
title_short Case report: Successful experience using continuous infusion of meropenem in a geriatric patient with hip fracture complicated by sepsis
title_sort case report successful experience using continuous infusion of meropenem in a geriatric patient with hip fracture complicated by sepsis
topic hip fracture
sepsis
pneumonia
continuous infusion
meropenem
case report
url https://www.frontiersin.org/articles/10.3389/fmed.2023.1148555/full
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