Concurrent silencing of TBCE and drug delivery to overcome platinum-based resistance in liver cancer

Concurrent silencing of TBCE and drug delivery to overcome platinum-based resistance in liver cancer

Platinum-based chemotherapy resistance is a key factor of poor prognosis and recurrence in hepatocellular carcinoma (HCC). Herein, RNAseq analysis revealed that elevated tubulin folding cofactor E (TBCE) expression is associated with platinum-based chemotherapy resistance. High expression of TBCE co...

Full description

Bibliographic Details
Main Authors: Senlin Li, Siyu Chen, Zhihui Dong, Xingdong Song, Xiuling Li, Ziqi Huang, Huiru Li, Linzhuo Huang, Ganyuan Zhuang, Ran Lan, Mingyan Guo, Wende Li, Phei Er Saw, Lei Zhang
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Hepatocellular carcinoma
Tubulin folding cofactor E
Chemoresistance
siRNA delivery
RNA interference
Nanoparticle
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383522001022

Internet

http://www.sciencedirect.com/science/article/pii/S2211383522001022

Similar Items