Compressive stenosis of the left hepatic vein as a pathogenesis of postresectional liver failure: a case report
<p>Abstract</p> <p>Introduction</p> <p>Postresectional liver failure (PLF) is a devastating and fatal complication of major hepatic resection, and we do not have a full understanding of the pathogenic mechanisms involved. No reliable treatment other than liver transplan...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2010-05-01
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| Series: | Journal of Medical Case Reports |
| Online Access: | http://www.jmedicalcasereports.com/content/4/1/163 |
| _version_ | 1819088507368374272 |
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| author | Ninomiya Mizuki Ikeda Tetsuo |
| author_facet | Ninomiya Mizuki Ikeda Tetsuo |
| author_sort | Ninomiya Mizuki |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Introduction</p> <p>Postresectional liver failure (PLF) is a devastating and fatal complication of major hepatic resection, and we do not have a full understanding of the pathogenic mechanisms involved. No reliable treatment other than liver transplantation currently exists for PLF.</p> <p>Case presentation</p> <p>A 46-year-old Japanese man experienced PLF after an extended right hepatectomy for liver malignancy. Seven months after surgery, the patient's Model for End-Stage Liver Disease (MELD) score had reached 23. Doppler ultrasound study and three-dimensional computed tomography images showed a stenosed left hepatic vein compressed by surrounding hypertrophied hepatic parenchyma. Transluminal balloon angioplasty and stent placement therapy were conducted eight months after surgery. The pressure gradient between the hepatic vein and right atrium decreased from 13 to 3 mmHg after stent placement. Thereafter, the patient recovered.</p> <p>Conclusion</p> <p>Hepatic venous compression by surrounding hypertrophied hepatic parenchyma might, at least in part, be associated with the occurrence of PLF. Surgeons should bear this possibility in mind when confronted with cases of PLF, as early diagnosis and stent placement improves patients' chances of recovery.</p> |
| first_indexed | 2024-12-21T21:53:08Z |
| format | Article |
| id | doaj.art-514c9c7d096f44df8cf27f749c9d3544 |
| institution | Directory Open Access Journal |
| issn | 1752-1947 |
| language | English |
| last_indexed | 2024-12-21T21:53:08Z |
| publishDate | 2010-05-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Medical Case Reports |
| spelling | doaj.art-514c9c7d096f44df8cf27f749c9d35442022-12-21T18:49:02ZengBMCJournal of Medical Case Reports1752-19472010-05-014116310.1186/1752-1947-4-163Compressive stenosis of the left hepatic vein as a pathogenesis of postresectional liver failure: a case reportNinomiya MizukiIkeda Tetsuo<p>Abstract</p> <p>Introduction</p> <p>Postresectional liver failure (PLF) is a devastating and fatal complication of major hepatic resection, and we do not have a full understanding of the pathogenic mechanisms involved. No reliable treatment other than liver transplantation currently exists for PLF.</p> <p>Case presentation</p> <p>A 46-year-old Japanese man experienced PLF after an extended right hepatectomy for liver malignancy. Seven months after surgery, the patient's Model for End-Stage Liver Disease (MELD) score had reached 23. Doppler ultrasound study and three-dimensional computed tomography images showed a stenosed left hepatic vein compressed by surrounding hypertrophied hepatic parenchyma. Transluminal balloon angioplasty and stent placement therapy were conducted eight months after surgery. The pressure gradient between the hepatic vein and right atrium decreased from 13 to 3 mmHg after stent placement. Thereafter, the patient recovered.</p> <p>Conclusion</p> <p>Hepatic venous compression by surrounding hypertrophied hepatic parenchyma might, at least in part, be associated with the occurrence of PLF. Surgeons should bear this possibility in mind when confronted with cases of PLF, as early diagnosis and stent placement improves patients' chances of recovery.</p>http://www.jmedicalcasereports.com/content/4/1/163 |
| spellingShingle | Ninomiya Mizuki Ikeda Tetsuo Compressive stenosis of the left hepatic vein as a pathogenesis of postresectional liver failure: a case report Journal of Medical Case Reports |
| title | Compressive stenosis of the left hepatic vein as a pathogenesis of postresectional liver failure: a case report |
| title_full | Compressive stenosis of the left hepatic vein as a pathogenesis of postresectional liver failure: a case report |
| title_fullStr | Compressive stenosis of the left hepatic vein as a pathogenesis of postresectional liver failure: a case report |
| title_full_unstemmed | Compressive stenosis of the left hepatic vein as a pathogenesis of postresectional liver failure: a case report |
| title_short | Compressive stenosis of the left hepatic vein as a pathogenesis of postresectional liver failure: a case report |
| title_sort | compressive stenosis of the left hepatic vein as a pathogenesis of postresectional liver failure a case report |
| url | http://www.jmedicalcasereports.com/content/4/1/163 |
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