Immunohistochemical expression of p53, BCL-2, BAX and VEGFR1 proteins in nephroblastomas A expressão imuno-histoquímica das proteínas p53, BCL-2, BAX e VEGFR1 em nefroblastomas

Immunohistochemical expression of p53, BCL-2, BAX and VEGFR1 proteins in nephroblastomas A expressão imuno-histoquímica das proteínas p53, BCL-2, BAX e VEGFR1 em nefroblastomas

INTRODUCTION: Nephroblastoma or Wilms' tumor is the most frequent renal cancer in children. Although its prognosis is favorable for most patients, it may relapse or have a fatal outcome. The characterization of risk groups by applying immunohistochemical biomarkers aims to adapt the treatment t...

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Bibliographic Details
Main Authors: Ana Paula Percicote, Fernanda El Ghoz Leme, Tammy Vernalha Rocha Almeida, Ana Karyn Ehrenfried Freitas, Elizabeth Schneider Gugelmin, Lúcia de Noronha
Format: Article
Language:English
Published: Sociedade Brasileira de Patologia Clínica 2013-02-01
Series:Jornal Brasileiro de Patologia e Medicina Laboratorial
Subjects:
tumor de Wilms
p53
BCL-2
BAX
VEGFR1
Wilms' tumor
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442013000100008

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442013000100008

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