Pd(II) Binding Strength of a Novel Ambidentate Dipeptide-Hydroxypyridinonate Ligand: A Solution Equilibrium Study

Pd(II) Binding Strength of a Novel Ambidentate Dipeptide-Hydroxypyridinonate Ligand: A Solution Equilibrium Study

A novel ambidentate dipeptide conjugate (H(L1)) containing N-donor atoms of the peptide part and an (O,O) chelate at the hydroxypyridinone (HP) ring is synthesized and characterized. It is hoped that this chelating ligand can be useful to obtain multitargeted Co(III)/Pt(II) dinuclear complexes with...

Full description

Bibliographic Details
Main Authors:	Linda Bíró, András Ozsváth, Réka Kapitány, Péter Buglyó
Format:	Article
Language:	English
Published:	MDPI AG 2022-07-01
Series:	Molecules
Subjects:	multitargeted palladium anticancer speciation stability constant ambidentate
Online Access:	https://www.mdpi.com/1420-3049/27/14/4667

Similar Items

Donor Atom Preference of Organoruthenium and Organorhodium Cations on the Interaction with Novel Ambidentate (N,N) and (O,O) Chelating Ligands in Aqueous Solution
by: Sándor Nagy, et al.
Published: (2021-06-01)

Deposition of exchange-coupled dinickel complexes on gold substrates utilizing ambidentate mercapto-carboxylato ligands
by: Martin Börner, et al.
Published: (2017-07-01)

Molecular structures of pyridinethiolato complexes of Sn(II), Sn(IV), Ge(IV), and Si(IV)
by: Wächtler Erik, et al.
Published: (2013-12-01)

Equilibrium Studies on Pd(II)–Amine Complexes with Bio-Relevant Ligands in Reference to Their Antitumor Activity
by: Mohamed M. Shoukry, et al.
Published: (2023-03-01)

Speciation and reaction equilibrium constant modelling of aqueous hydrometallurgical systems at elevated temperatures: A review
by: Okechukwu Vincent Dickson, et al.
Published: (2023-09-01)

Direct cellular targets and anticancer mechanisms of the natural product oridonin
by: Jialin Yao, et al.
Published: (2023-03-01)

Influence of the model used for the calculation of equilibrium constants at moderate temperature for electrolytes
by: Dickson Okechukwu V., et al.
Published: (2023-01-01)

Comparative Solution Equilibrium Studies on Anticancer Estradiol-Based Conjugates and Their Copper Complexes
by: Éva A. Enyedy, et al.
Published: (2024-02-01)

MULTITARGET ANTI-PD-1/PD-L1/CD19/CD25/CD38 THERAPY USING CHELATE NANOCOMPLEX MSC-428 IN ONCOPATHOLOGY
by: Lukyanchuk O. V., et al.
Published: (2018-12-01)

Multitargeting approaches involving carbonic anhydrase inhibitors: hybrid drugs against a variety of disorders
by: Claudiu T. Supuran
Published: (2021-01-01)

Novel Phenolic Compounds as Potential Dual EGFR and COX-2 Inhibitors: Design, Semisynthesis, in vitro Biological Evaluation and in silico Insights
by: Abdelgawad MA, et al.
Published: (2021-05-01)

Anticancer Activity and Cisplatin Binding Ability of Bis-Quinoline and Bis-Isoquinoline Derived [Pd2L4]4+ Metallosupramolecular Cages
by: Roan A. S. Vasdev, et al.
Published: (2018-11-01)

A Definition of “Multitargeticity”: Identifying Potential Multitarget and Selective Ligands Through a Vector Analysis
by: Juan Francisco Sánchez-Tejeda, et al.
Published: (2020-03-01)

Spectroscopic, anticancer and antioxidant studies of fluxional trans-[PdCl2(S-acylthiourea)2] complexes
by: Dorothy Priyanka Dorairaj, et al.
Published: (2021-01-01)

THE INFLUENCE OF THE NATURE OF ALCOHOLS ON THE FORMATION OF PALLADIUM NANOPARTICLES IN THE SYSTEM PdCl2–NaCl–H2O
by: E. A. Bakhtieva, et al.
Published: (2013-08-01)

Intrinsic Effect of Pyridine-N-Position on Structural Properties of Cu-Based Low-Dimensional Coordination Frameworks
by: Anna Walczak, et al.
Published: (2020-08-01)

Easily synthesizable benzothiazole based designers palladium complexes for catalysis of Suzuki coupling: Controlling effect of aryl substituent of ligand on role and composition of insitu generated binary nanomaterial (PdS or Pd16S7)
by: Preeti Oswal, et al.
Published: (2021-01-01)

Hydroxypyridinone-Based Metal Chelators towards Ecotoxicity: Remediation and Biological Mechanisms
by: M. Amélia Santos, et al.
Published: (2022-03-01)

Studies on Nickel(II)-Pyridoxamine-Imidazole Containing Mixed Ligand Complex Systems
by: M.A Neelakantan, et al.
Published: (2004-04-01)

Kinetics characteristics of dissolving PdCl<sub>2</sub> in water-chlorid solutions
by: A. V. Krylov, et al.
Published: (2014-12-01)

Editorial: Recent advances in the research and development of kinase-inhibitory anticancer molecules
by: Ahmed A. Al-Karmalawy, et al.
Published: (2023-11-01)

Platinum and Palladium Complexes as Promising Sources for Antitumor Treatments
by: Robert Czarnomysy, et al.
Published: (2021-07-01)

Synthesis methods and applications of palladium nanoparticles: A review
by: Nadeem Joudeh, et al.
Published: (2022-11-01)

Solution Equilibrium Studies on Salicylidene Aminoguanidine Schiff Base Metal Complexes: Impact of the Hybridization with L-Proline on Stability, Redox Activity and Cytotoxicity
by: Orsolya Dömötör, et al.
Published: (2022-03-01)

Half-Sandwich Rhodium Complexes with Releasable N-Donor Monodentate Ligands: Solution Chemical Properties and the Possibility for Acidosis Activation
by: János P. Mészáros, et al.
Published: (2023-01-01)

Beyond the Canonical Endocannabinoid System. A Screening of PPAR Ligands as FAAH Inhibitors
by: Leonardo Brunetti, et al.
Published: (2020-09-01)

Study of the anticancer effect of new quinazolinone hydrazine derivatives as receptor tyrosine kinase inhibitors
by: Motahareh Mortazavi, et al.
Published: (2022-11-01)

Homo- and Heteropolymetallic Complexes of the Hybrid, Ambidentate N‑Heterocyclic Carbene Ligand IMes-acac
by: Vincent César, et al.
Published: (2018-11-01)

Ligand-Tuning of the Stability of Pd(II) Conjugates with Cyanocobalamin
by: Dominika Porębska, et al.
Published: (2021-07-01)

Kinetics of the Lattice Response to Hydrogen Absorption in Thin Pd and CoPd Films
by: Sudhansu Sekhar Das, et al.
Published: (2020-08-01)

Synthesis and antileishmanial activity of antimony (V) complexes of hydroxypyranone and hydroxypyridinone ligands
by: Vafa Sheikhmoradi, et al.
Published: (2018-01-01)

2-Phosphonobutane-1,2,4,-Tricarboxylic Acid (PBTC): pH-Dependent Behavior Studied by Means of Multinuclear NMR Spectroscopy
by: Jerome Kretzschmar, et al.
Published: (2022-06-01)

Catalytic activity of Pd-Ni in the oxidation of hydrogen for the safety of nuclear power plant
by: Łomot Dariusz, et al.
Published: (2016-03-01)

(μ-Methylenediphosphonato-κ4O,O′:O′′,O′′′)bis[(ethylenediamine-κ2N,N′)palladium(II)] tetrahydrate
by: Viktoriya V. Dyakonenko, et al.
Published: (2018-12-01)

<b>Drop amalgam voltammetric study of lead complexation by natural inorganic ligands in a salt lake</b>
by: Muhammad Ntale, et al.
Published: (2004-06-01)

Electrochemical behavior of electrodeposited Pd and PdNi coatings for the ethanol oxidation reaction in alkaline solution
by: Jelena DuÅ¡an Lović, et al.
Published: (2018-03-01)

Novel platinum–palladium bimetallic nanoparticles synthesized by Dioscorea bulbifera: anticancer and antioxidant activities
by: Ghosh S, et al.
Published: (2015-12-01)

The Effect of Pd on electrical properties of Sn02 in CH4 detection /
by: 207142 Dennis, John Ojur
Published: (2001)

Corrigendum: Discovery of spirooxindole-derived small-molecule compounds as novel HDAC/MDM2 dual inhibitors and investigation of their anticancer activity
by: Qian Zhao, et al.
Published: (2023-08-01)

Discovery of spirooxindole-derived small-molecule compounds as novel HDAC/MDM2 dual inhibitors and investigation of their anticancer activity
by: Qian Zhao, et al.
Published: (2022-08-01)