Fatty Acid Binding Domain Mediated Conjugation of Ultrafine Magnetic Nanoparticles with Albumin Protein
<p>Abstract</p> <p>A novel bioconjugate of stearic acid capped maghemite nanoparticle (γ-Fe<sub>2</sub>O<sub>3</sub>) with bovine serum albumin (BSA) was developed by taking recourse to the fatty acid binding property of the protein. From FT-IR stud...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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SpringerOpen
2008-01-01
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| Series: | Nanoscale Research Letters |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1007/s11671-008-9213-6 |
| _version_ | 1797762450642173952 |
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| author | Bora DK Deb P |
| author_facet | Bora DK Deb P |
| author_sort | Bora DK |
| collection | DOAJ |
| description | <p>Abstract</p> <p>A novel bioconjugate of stearic acid capped maghemite nanoparticle (γ-Fe<sub>2</sub>O<sub>3</sub>) with bovine serum albumin (BSA) was developed by taking recourse to the fatty acid binding property of the protein. From FT-IR study, it was found that conjugation took place covalently between the amine group of protein molecule and carboxyl group of stearic acid capped maghemite nanoparticle. TEM study further signified the morphology of the proposed nanobioconjuagte. The binding constant of nanoparticle with protein molecule was evaluated from the optical property studies. Also, magnetic measurement (M–H) showed retaining of magnetic property by significant values of saturation magnetization and other hysteretic parameters.</p> |
| first_indexed | 2024-03-12T19:28:29Z |
| format | Article |
| id | doaj.art-514fb59f209a4416a871206a1defaac4 |
| institution | Directory Open Access Journal |
| issn | 1931-7573 1556-276X |
| language | English |
| last_indexed | 2024-03-12T19:28:29Z |
| publishDate | 2008-01-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | Nanoscale Research Letters |
| spelling | doaj.art-514fb59f209a4416a871206a1defaac42023-08-02T04:46:04ZengSpringerOpenNanoscale Research Letters1931-75731556-276X2008-01-0142138143Fatty Acid Binding Domain Mediated Conjugation of Ultrafine Magnetic Nanoparticles with Albumin ProteinBora DKDeb P<p>Abstract</p> <p>A novel bioconjugate of stearic acid capped maghemite nanoparticle (γ-Fe<sub>2</sub>O<sub>3</sub>) with bovine serum albumin (BSA) was developed by taking recourse to the fatty acid binding property of the protein. From FT-IR study, it was found that conjugation took place covalently between the amine group of protein molecule and carboxyl group of stearic acid capped maghemite nanoparticle. TEM study further signified the morphology of the proposed nanobioconjuagte. The binding constant of nanoparticle with protein molecule was evaluated from the optical property studies. Also, magnetic measurement (M–H) showed retaining of magnetic property by significant values of saturation magnetization and other hysteretic parameters.</p>http://dx.doi.org/10.1007/s11671-008-9213-6BioconjugateMaghemite nanoparticleBovine serum albuminCovalent interactionFatty acid binding domain |
| spellingShingle | Bora DK Deb P Fatty Acid Binding Domain Mediated Conjugation of Ultrafine Magnetic Nanoparticles with Albumin Protein Nanoscale Research Letters Bioconjugate Maghemite nanoparticle Bovine serum albumin Covalent interaction Fatty acid binding domain |
| title | Fatty Acid Binding Domain Mediated Conjugation of Ultrafine Magnetic Nanoparticles with Albumin Protein |
| title_full | Fatty Acid Binding Domain Mediated Conjugation of Ultrafine Magnetic Nanoparticles with Albumin Protein |
| title_fullStr | Fatty Acid Binding Domain Mediated Conjugation of Ultrafine Magnetic Nanoparticles with Albumin Protein |
| title_full_unstemmed | Fatty Acid Binding Domain Mediated Conjugation of Ultrafine Magnetic Nanoparticles with Albumin Protein |
| title_short | Fatty Acid Binding Domain Mediated Conjugation of Ultrafine Magnetic Nanoparticles with Albumin Protein |
| title_sort | fatty acid binding domain mediated conjugation of ultrafine magnetic nanoparticles with albumin protein |
| topic | Bioconjugate Maghemite nanoparticle Bovine serum albumin Covalent interaction Fatty acid binding domain |
| url | http://dx.doi.org/10.1007/s11671-008-9213-6 |
| work_keys_str_mv | AT boradk fattyacidbindingdomainmediatedconjugationofultrafinemagneticnanoparticleswithalbuminprotein AT debp fattyacidbindingdomainmediatedconjugationofultrafinemagneticnanoparticleswithalbuminprotein |