An In-vitro Comparison of Nano Hydroxyapatite, Novamin and Proargin Desensitizing Toothpastes - A SEM Study

Introduction: Dentinal Hypersensitivity (DH) is commonly encountered clinical condition in dental practice which affects 8-57% of the adult population presenting for dental treatment, but the treatment of the same remains doubtful. Aim: The purpose of this study was to evaluate and compare the...

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Main Authors: RITHESH KULAL, IPSITA JAYANTI, SAVITA SAMBASHIVAIAH, SHIVAPRASAD BILCHODMATH
Format: Article
Language:English
Published: JCDR Research and Publications Private Limited 2016-10-01
Series:Journal of Clinical and Diagnostic Research
Subjects:
Online Access:https://jcdr.net/articles/PDF/8649/18991_CE(EK)_F(AK)_PF1(NEAK)_PFA(AK).pdf
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author RITHESH KULAL
IPSITA JAYANTI
SAVITA SAMBASHIVAIAH
SHIVAPRASAD BILCHODMATH
author_facet RITHESH KULAL
IPSITA JAYANTI
SAVITA SAMBASHIVAIAH
SHIVAPRASAD BILCHODMATH
author_sort RITHESH KULAL
collection DOAJ
description Introduction: Dentinal Hypersensitivity (DH) is commonly encountered clinical condition in dental practice which affects 8-57% of the adult population presenting for dental treatment, but the treatment of the same remains doubtful. Aim: The purpose of this study was to evaluate and compare the effects of three different desensitizing agents (15% nano hydroxyapatite crystals; 5% novamin and 8% proargin) on dentinal permeability and tubule occlusion in-vitro. Scanning Electron Microscope (SEM) was used to evaluate the effect of these commercially available desensitizing toothpastes. Materials and Methods: A total of 40 disc shaped dentin specimens were dissected from extracted premolars. Dentin discs of 1mm were obtained with the help of diamond discs. Ten specimens were randomly selected and allocated to the evaluation groups A (control group), B (Nano-hydroxyapatite), C (Novamin) and D (Proargin). Each treatment group dentine disc specimen was treated with the respective slurry for two minutes for a period of seven days. Each disc was subjected to a pre- and post-treatment SEM analysis to evaluate the changes occurring in the dentinal tubules. Results: The qualitative analysis showed no occlusion of the dentinal tubules in Group A (control group) and Group B (nanohydroxyapatite) showed 98.1% tubule occlusion. Group C (Novamin) and D (Proargin) showed 83.1% and 69.1% tubule occlusion respectively. Quantitative analysis showed a statistical significant difference between Group B and D (p< 0.005) and no statistical significant difference between group B and C (p= 0.235). Similarly, there was no significant difference between Group C and D as (p=0.235). Conclusion: It was concluded that all the three desensiting agents were effective in the dentine tubule occlusion. In addition efficacy of nano-hydroxyapatite toothpaste was greater compared to the other desensiting agents.
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spelling doaj.art-5151b041374c43849ba000e2d30c79352022-12-21T19:15:10ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2016-10-011010ZC51ZC5410.7860/JCDR/2016/18991.8649An In-vitro Comparison of Nano Hydroxyapatite, Novamin and Proargin Desensitizing Toothpastes - A SEM StudyRITHESH KULAL0IPSITA JAYANTI1SAVITA SAMBASHIVAIAH2SHIVAPRASAD BILCHODMATH3Reader, Department of Periodontology, Rajarajeswari Dental College and Hospital, Bengaluru, Karnataka, India.Lecturer, Department of Periodontics and Oral Implantology, Kalinga Institute of Dental Sciences, Bhubaneswar, Odisha, India.Professor and HOD, Department of Periodontology, Rajarajeswari Dental College and Hospital, Bengaluru, Karnataka, India.Reader, Department of Periodontology, Rajarajeswari Dental College and Hospital, Bengaluru, Karnataka, India.Introduction: Dentinal Hypersensitivity (DH) is commonly encountered clinical condition in dental practice which affects 8-57% of the adult population presenting for dental treatment, but the treatment of the same remains doubtful. Aim: The purpose of this study was to evaluate and compare the effects of three different desensitizing agents (15% nano hydroxyapatite crystals; 5% novamin and 8% proargin) on dentinal permeability and tubule occlusion in-vitro. Scanning Electron Microscope (SEM) was used to evaluate the effect of these commercially available desensitizing toothpastes. Materials and Methods: A total of 40 disc shaped dentin specimens were dissected from extracted premolars. Dentin discs of 1mm were obtained with the help of diamond discs. Ten specimens were randomly selected and allocated to the evaluation groups A (control group), B (Nano-hydroxyapatite), C (Novamin) and D (Proargin). Each treatment group dentine disc specimen was treated with the respective slurry for two minutes for a period of seven days. Each disc was subjected to a pre- and post-treatment SEM analysis to evaluate the changes occurring in the dentinal tubules. Results: The qualitative analysis showed no occlusion of the dentinal tubules in Group A (control group) and Group B (nanohydroxyapatite) showed 98.1% tubule occlusion. Group C (Novamin) and D (Proargin) showed 83.1% and 69.1% tubule occlusion respectively. Quantitative analysis showed a statistical significant difference between Group B and D (p< 0.005) and no statistical significant difference between group B and C (p= 0.235). Similarly, there was no significant difference between Group C and D as (p=0.235). Conclusion: It was concluded that all the three desensiting agents were effective in the dentine tubule occlusion. In addition efficacy of nano-hydroxyapatite toothpaste was greater compared to the other desensiting agents.https://jcdr.net/articles/PDF/8649/18991_CE(EK)_F(AK)_PF1(NEAK)_PFA(AK).pdfbioactive glassbiomaterialsdentin hypersensitivitydentin disc
spellingShingle RITHESH KULAL
IPSITA JAYANTI
SAVITA SAMBASHIVAIAH
SHIVAPRASAD BILCHODMATH
An In-vitro Comparison of Nano Hydroxyapatite, Novamin and Proargin Desensitizing Toothpastes - A SEM Study
Journal of Clinical and Diagnostic Research
bioactive glass
biomaterials
dentin hypersensitivity
dentin disc
title An In-vitro Comparison of Nano Hydroxyapatite, Novamin and Proargin Desensitizing Toothpastes - A SEM Study
title_full An In-vitro Comparison of Nano Hydroxyapatite, Novamin and Proargin Desensitizing Toothpastes - A SEM Study
title_fullStr An In-vitro Comparison of Nano Hydroxyapatite, Novamin and Proargin Desensitizing Toothpastes - A SEM Study
title_full_unstemmed An In-vitro Comparison of Nano Hydroxyapatite, Novamin and Proargin Desensitizing Toothpastes - A SEM Study
title_short An In-vitro Comparison of Nano Hydroxyapatite, Novamin and Proargin Desensitizing Toothpastes - A SEM Study
title_sort in vitro comparison of nano hydroxyapatite novamin and proargin desensitizing toothpastes a sem study
topic bioactive glass
biomaterials
dentin hypersensitivity
dentin disc
url https://jcdr.net/articles/PDF/8649/18991_CE(EK)_F(AK)_PF1(NEAK)_PFA(AK).pdf
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