Encorafenib plus cetuximab for the treatment of -mutated metastatic colorectal cancer

B-type RAF ( BRAF ) -V600E mutations in metastatic colorectal cancer (mCRC) have been described in up to 12% of the patients. This mutation confers a bad prognostic and poor response with standard chemotherapy. Unlike the scenario for BRAF mutant melanoma, successful BRAF blockade in mCRC has emerge...

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Détails bibliographiques
Auteurs principaux: Javier Ros, Nadia Saoudi, Iosune Baraibar, Francesc Salva, Josep Tabernero, Elena Elez
Format: Article
Langue:English
Publié: SAGE Publishing 2022-07-01
Collection:Therapeutic Advances in Gastroenterology
Accès en ligne:https://doi.org/10.1177/17562848221110644