Self-Renewing Trophoblast Organoids Recapitulate the Developmental Program of the Early Human Placenta

Self-Renewing Trophoblast Organoids Recapitulate the Developmental Program of the Early Human Placenta

Summary: Defective placentation is the underlying cause of various pregnancy complications, such as severe intrauterine growth restriction and preeclampsia. However, studies on human placental development are hampered by the lack of a self-renewing in vitro model that would recapitulate formation of...

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Main Authors: Sandra Haider, Gudrun Meinhardt, Leila Saleh, Viktoria Kunihs, Magdalena Gamperl, Ulrich Kaindl, Adolf Ellinger, Thomas R. Burkard, Christian Fiala, Jürgen Pollheimer, Sasha Mendjan, Paulina A. Latos, Martin Knöfler
Format: Article
Language:English
Published: Elsevier 2018-08-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671118303096

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