Utilisation patterns and costs of lipid-lowering drugs in Switzerland 2013–2019

OBJECTIVE: To analyse utilisation patterns of lipid-lowering drugs and the related costs in Switzerland between the years 2013 and 2019. METHODS: We conducted a retrospective descriptive study using administrative claims data of persons aged ≥18 years enrolled with the health insurance company H...

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Main Authors: Daphne Reinau , Nadine Schur, Sibylle Twerenbold , Eva Blozik , Mathias Früh, Andri Signorell, Matthias Schwenkglenks , Christoph R. Meier
Format: Article
Language:English
Published: SMW supporting association (Trägerverein Swiss Medical Weekly SMW) 2021-09-01
Series:Swiss Medical Weekly
Online Access:https://www.smw.ch/index.php/smw/article/view/3060
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author Daphne Reinau 
Nadine Schur
Sibylle Twerenbold 
Eva Blozik 
Mathias Früh
Andri Signorell
Matthias Schwenkglenks 
Christoph R. Meier
author_facet Daphne Reinau 
Nadine Schur
Sibylle Twerenbold 
Eva Blozik 
Mathias Früh
Andri Signorell
Matthias Schwenkglenks 
Christoph R. Meier
author_sort Daphne Reinau 
collection DOAJ
description OBJECTIVE: To analyse utilisation patterns of lipid-lowering drugs and the related costs in Switzerland between the years 2013 and 2019. METHODS: We conducted a retrospective descriptive study using administrative claims data of persons aged ≥18 years enrolled with the health insurance company Helsana. To enable statements at the Swiss population level, results were extrapolated according to age, sex and canton of residence. RESULTS: The overall prevalence of patients taking lipid-lowering drugs rose from 8.9% (n = 736,174) in 2013 to 11.6% (n = 841,682) in 2019, but varied markedly across regions, with highest values in Ticino and lowest values in Zurich. More than every third individual aged ≥65 years was treated with a lipid-lowering drug in 2019. Statins were by far the most commonly used drugs (>90% of prescriptions), followed by ezetimibe, fibrates and PCSK9 inhibitors. We observed a trend towards the prescription of more potent statins (atorvastatin, rosuvastatin) in recent years. Total costs of lipid-lowering drugs increased from CHF 222 million in 2013 to CHF 230 million in 2019 (+3.5%), whereas annual per capita costs decreased from CHF 302 in 2013 to CHF 273 in 2019 (−9.4%). CONCLUSION: The increasing use of lipid-lowering drugs reflects current therapeutic guidelines, but results in high costs for the healthcare system.
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spelling doaj.art-515ebac10f0e475190d902a29f9155cf2022-12-29T16:01:20ZengSMW supporting association (Trägerverein Swiss Medical Weekly SMW)Swiss Medical Weekly1424-39972021-09-01151353610.4414/SMW.2021.w30018Utilisation patterns and costs of lipid-lowering drugs in Switzerland 2013–2019Daphne Reinau Nadine SchurSibylle Twerenbold Eva Blozik Mathias FrühAndri SignorellMatthias Schwenkglenks Christoph R. Meier OBJECTIVE: To analyse utilisation patterns of lipid-lowering drugs and the related costs in Switzerland between the years 2013 and 2019. METHODS: We conducted a retrospective descriptive study using administrative claims data of persons aged ≥18 years enrolled with the health insurance company Helsana. To enable statements at the Swiss population level, results were extrapolated according to age, sex and canton of residence. RESULTS: The overall prevalence of patients taking lipid-lowering drugs rose from 8.9% (n = 736,174) in 2013 to 11.6% (n = 841,682) in 2019, but varied markedly across regions, with highest values in Ticino and lowest values in Zurich. More than every third individual aged ≥65 years was treated with a lipid-lowering drug in 2019. Statins were by far the most commonly used drugs (>90% of prescriptions), followed by ezetimibe, fibrates and PCSK9 inhibitors. We observed a trend towards the prescription of more potent statins (atorvastatin, rosuvastatin) in recent years. Total costs of lipid-lowering drugs increased from CHF 222 million in 2013 to CHF 230 million in 2019 (+3.5%), whereas annual per capita costs decreased from CHF 302 in 2013 to CHF 273 in 2019 (−9.4%). CONCLUSION: The increasing use of lipid-lowering drugs reflects current therapeutic guidelines, but results in high costs for the healthcare system. https://www.smw.ch/index.php/smw/article/view/3060
spellingShingle Daphne Reinau 
Nadine Schur
Sibylle Twerenbold 
Eva Blozik 
Mathias Früh
Andri Signorell
Matthias Schwenkglenks 
Christoph R. Meier
Utilisation patterns and costs of lipid-lowering drugs in Switzerland 2013–2019
Swiss Medical Weekly
title Utilisation patterns and costs of lipid-lowering drugs in Switzerland 2013–2019
title_full Utilisation patterns and costs of lipid-lowering drugs in Switzerland 2013–2019
title_fullStr Utilisation patterns and costs of lipid-lowering drugs in Switzerland 2013–2019
title_full_unstemmed Utilisation patterns and costs of lipid-lowering drugs in Switzerland 2013–2019
title_short Utilisation patterns and costs of lipid-lowering drugs in Switzerland 2013–2019
title_sort utilisation patterns and costs of lipid lowering drugs in switzerland 2013 2019
url https://www.smw.ch/index.php/smw/article/view/3060
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