Molecular and genetic aspects of essential arterial hypertension in children
The article presents the results of clinical, molecular genetic data on the role of polymorphism of renin-angiotensin system genes ADD1, AGT, AGTR1, AGTR2, CYP11B2, GNB3, NOS3 in children with essential hypertension, taking into account the results of 24-hour blood pressure monitoring. The main Grou...
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Format: | Article |
Language: | Russian |
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Ltd. “The National Academy of Pediatric Science and Innovation”
2020-11-01
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Series: | Rossijskij Vestnik Perinatologii i Pediatrii |
Subjects: | |
Online Access: | https://www.ped-perinatology.ru/jour/article/view/1237 |
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author | G. A. Ignatenko D. O. Lastkov A. V. Dubovaya Yu. V. Naumenko |
author_facet | G. A. Ignatenko D. O. Lastkov A. V. Dubovaya Yu. V. Naumenko |
author_sort | G. A. Ignatenko |
collection | DOAJ |
description | The article presents the results of clinical, molecular genetic data on the role of polymorphism of renin-angiotensin system genes ADD1, AGT, AGTR1, AGTR2, CYP11B2, GNB3, NOS3 in children with essential hypertension, taking into account the results of 24-hour blood pressure monitoring. The main Group consisted of 16 children (13 boys and 3 girls) aged from 13 to 17 years with essential arterial hypertension. The results of the study indicate a significant contribution of genetic factors to the development and progression of arterial hypertension in children. |
first_indexed | 2024-04-10T01:42:13Z |
format | Article |
id | doaj.art-515ecec495d7491287f10ec8b1c62809 |
institution | Directory Open Access Journal |
issn | 1027-4065 2500-2228 |
language | Russian |
last_indexed | 2024-04-10T01:42:13Z |
publishDate | 2020-11-01 |
publisher | Ltd. “The National Academy of Pediatric Science and Innovation” |
record_format | Article |
series | Rossijskij Vestnik Perinatologii i Pediatrii |
spelling | doaj.art-515ecec495d7491287f10ec8b1c628092023-03-13T09:12:49ZrusLtd. “The National Academy of Pediatric Science and Innovation”Rossijskij Vestnik Perinatologii i Pediatrii1027-40652500-22282020-11-01655545710.21508/1027-4065-2020-65-5-54-57937Molecular and genetic aspects of essential arterial hypertension in childrenG. A. Ignatenko0D. O. Lastkov1A. V. Dubovaya2Yu. V. Naumenko3ГОО ВПО Донецкий национальный медицинский университет им. М. ГорькогоГОО ВПО Донецкий национальный медицинский университет им. М. ГорькогоГОО ВПО Донецкий национальный медицинский университет им. М. ГорькогоГОО ВПО Донецкий национальный медицинский университет им. М. Горького; Институт неотложной и восстановительной хирургии им. В.К. ГусакаThe article presents the results of clinical, molecular genetic data on the role of polymorphism of renin-angiotensin system genes ADD1, AGT, AGTR1, AGTR2, CYP11B2, GNB3, NOS3 in children with essential hypertension, taking into account the results of 24-hour blood pressure monitoring. The main Group consisted of 16 children (13 boys and 3 girls) aged from 13 to 17 years with essential arterial hypertension. The results of the study indicate a significant contribution of genetic factors to the development and progression of arterial hypertension in children.https://www.ped-perinatology.ru/jour/article/view/1237детиэссенциальная артериальная гипертензияполиморфизм геновadd1agtagtr1agtr2cyp11b2gnb3nos3 |
spellingShingle | G. A. Ignatenko D. O. Lastkov A. V. Dubovaya Yu. V. Naumenko Molecular and genetic aspects of essential arterial hypertension in children Rossijskij Vestnik Perinatologii i Pediatrii дети эссенциальная артериальная гипертензия полиморфизм генов add1 agt agtr1 agtr2 cyp11b2 gnb3 nos3 |
title | Molecular and genetic aspects of essential arterial hypertension in children |
title_full | Molecular and genetic aspects of essential arterial hypertension in children |
title_fullStr | Molecular and genetic aspects of essential arterial hypertension in children |
title_full_unstemmed | Molecular and genetic aspects of essential arterial hypertension in children |
title_short | Molecular and genetic aspects of essential arterial hypertension in children |
title_sort | molecular and genetic aspects of essential arterial hypertension in children |
topic | дети эссенциальная артериальная гипертензия полиморфизм генов add1 agt agtr1 agtr2 cyp11b2 gnb3 nos3 |
url | https://www.ped-perinatology.ru/jour/article/view/1237 |
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