Antioxidant network-based signatures cluster glioblastoma into distinct redox-resistant phenotypes

Antioxidant network-based signatures cluster glioblastoma into distinct redox-resistant phenotypes

IntroductionAberrant reactive oxygen species (ROS) production is one of the hallmarks of cancer. During their growth and dissemination, cancer cells control redox signaling to support protumorigenic pathways. As a consequence, cancer cells become reliant on major antioxidant systems to maintain a b...

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Bibliographic Details
Main Authors: Yihan Yang, Sanket More, Frederik De Smet, Steven De Vleeschouwer, Patrizia Agostinis
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Immunology
Subjects:
oxidative stress
GBM
bioinformatics
antioxidant phenotype
signatures
canonical GBM classification
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1342977/full

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