Synthesis of novel nano-radiotracer for in-vivo bone imaging: 99mTc- citric acid based PEG dendrimer and its conjugation with alendronate

Synthesis of novel nano-radiotracer for in-vivo bone imaging: 99mTc- citric acid based PEG dendrimer and its conjugation with alendronate

Bone scan is the test that guide physician to diagnose diseases in the bone at the early stage, to prevent metastases to other organs. In this study, citric acid dendrimer conjugation with alendronate was synthesized. Obtained product was confirmed by FT-IR and TEM. Cytotoxicity assay at different c...

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Bibliographic Details
Main Authors: Behnam davoodikia, Morteza Pirali Hamedani, Mostafa Saffari, Seyed Esmaeil Sadat Ebrahimi, Mohammad Seyyed hamzeh, Shaghayegh Hashemi, Mehdi Shafiee Ardestani, Seyedeh Masoumeh Ghoreishi
Format: Article
Language:English
Published: Elsevier 2022-09-01
Series:Arabian Journal of Chemistry
Subjects:
Citric acid dendrimer
Alendronate
Bone scan
Radiolabeling
SPECT
MDP
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535222003768

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http://www.sciencedirect.com/science/article/pii/S1878535222003768

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