HIV-1 tropism testing in subjects achieving undetectable HIV-1 RNA: diagnostic accuracy, viral evolution and compartmentalization.

HIV-1 tropism testing in subjects achieving undetectable HIV-1 RNA: diagnostic accuracy, viral evolution and compartmentalization.

BACKGROUND: Technically, HIV-1 tropism can be evaluated in plasma or peripheral blood mononuclear cells (PBMCs). However, only tropism testing of plasma HIV-1 has been validated as a tool to predict virological response to CCR5 antagonists in clinical trials. The preferable tropism testing strategy...

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Main Authors: Christian Pou, Francisco M Codoñer, Alexander Thielen, Rocío Bellido, Susana Pérez-Álvarez, Cecilia Cabrera, Judith Dalmau, Marta Curriu, Yolanda Lie, Marc Noguera-Julian, Jordi Puig, Javier Martínez-Picado, Julià Blanco, Eoin Coakley, Martin Däumer, Bonaventura Clotet, Roger Paredes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3731261?pdf=render

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