A Combined Algorithm for Optimization: Application for Optimization of the Transition Gas-Liquid in Stirred Tank Bioreactors
A combined algorithm for static optimization is developed. The algorithm includes a method for random search of optimal an initial point and a method based on fuzzy sets theory, combined in order to be found for the best solution of the optimization problem. The application of the combined algorithm...
Main Author: | |
---|---|
Format: | Article |
Language: | English |
Published: |
Academic Publishing House
2005-12-01
|
Series: | Bioautomation |
Subjects: | |
Online Access: | http://www.clbme.bas.bg/bioautomation/2005/vol_3.1/files/3_1.2.pdf |
_version_ | 1818212426761371648 |
---|---|
author | Mitko Petrov |
author_facet | Mitko Petrov |
author_sort | Mitko Petrov |
collection | DOAJ |
description | A combined algorithm for static optimization is developed. The algorithm includes a method for random search of optimal an initial point and a method based on fuzzy sets theory, combined in order to be found for the best solution of the optimization problem. The application of the combined algorithm eliminates the main disadvantage of the used fuzzy optimization method, namely decreases the number of discrete values of control variables. In this way, the algorithm allows problems with larger scale to be solved. The combined algorithm is used for optimization of gas-liquid transition in dependence on some constructive and regime parameters of a laboratory scale stirred tank bioreactor. After the application of developed optimization algorithm significant increase of mass-transfer effectiveness, aeration and mixing processes in the bioreactor are observed. |
first_indexed | 2024-12-12T05:48:13Z |
format | Article |
id | doaj.art-5169560d82c647e0acd55637c04e8dac |
institution | Directory Open Access Journal |
issn | 1313-261X 1312-451X |
language | English |
last_indexed | 2024-12-12T05:48:13Z |
publishDate | 2005-12-01 |
publisher | Academic Publishing House |
record_format | Article |
series | Bioautomation |
spelling | doaj.art-5169560d82c647e0acd55637c04e8dac2022-12-22T00:35:45ZengAcademic Publishing HouseBioautomation1313-261X1312-451X2005-12-01311018A Combined Algorithm for Optimization: Application for Optimization of the Transition Gas-Liquid in Stirred Tank BioreactorsMitko PetrovA combined algorithm for static optimization is developed. The algorithm includes a method for random search of optimal an initial point and a method based on fuzzy sets theory, combined in order to be found for the best solution of the optimization problem. The application of the combined algorithm eliminates the main disadvantage of the used fuzzy optimization method, namely decreases the number of discrete values of control variables. In this way, the algorithm allows problems with larger scale to be solved. The combined algorithm is used for optimization of gas-liquid transition in dependence on some constructive and regime parameters of a laboratory scale stirred tank bioreactor. After the application of developed optimization algorithm significant increase of mass-transfer effectiveness, aeration and mixing processes in the bioreactor are observed.http://www.clbme.bas.bg/bioautomation/2005/vol_3.1/files/3_1.2.pdf Combined algorithmOptimizationGas-liquid transitionFuzzy sets theoryMethod of random search with back stepsFuzzy optimization |
spellingShingle | Mitko Petrov A Combined Algorithm for Optimization: Application for Optimization of the Transition Gas-Liquid in Stirred Tank Bioreactors Bioautomation Combined algorithm Optimization Gas-liquid transition Fuzzy sets theory Method of random search with back steps Fuzzy optimization |
title | A Combined Algorithm for Optimization: Application for Optimization of the Transition Gas-Liquid in Stirred Tank Bioreactors |
title_full | A Combined Algorithm for Optimization: Application for Optimization of the Transition Gas-Liquid in Stirred Tank Bioreactors |
title_fullStr | A Combined Algorithm for Optimization: Application for Optimization of the Transition Gas-Liquid in Stirred Tank Bioreactors |
title_full_unstemmed | A Combined Algorithm for Optimization: Application for Optimization of the Transition Gas-Liquid in Stirred Tank Bioreactors |
title_short | A Combined Algorithm for Optimization: Application for Optimization of the Transition Gas-Liquid in Stirred Tank Bioreactors |
title_sort | combined algorithm for optimization application for optimization of the transition gas liquid in stirred tank bioreactors |
topic | Combined algorithm Optimization Gas-liquid transition Fuzzy sets theory Method of random search with back steps Fuzzy optimization |
url | http://www.clbme.bas.bg/bioautomation/2005/vol_3.1/files/3_1.2.pdf |
work_keys_str_mv | AT mitkopetrov acombinedalgorithmforoptimizationapplicationforoptimizationofthetransitiongasliquidinstirredtankbioreactors AT mitkopetrov combinedalgorithmforoptimizationapplicationforoptimizationofthetransitiongasliquidinstirredtankbioreactors |