Circulating Microvesicles in Association with the NLRP3 Inflammasome in Coronary Thrombi from STEMI Patients

Circulating Microvesicles in Association with the NLRP3 Inflammasome in Coronary Thrombi from STEMI Patients

Microvesicles (MVs) are actively secreted by cells. The NLRP3-inflammasome and the interleukin 6 (IL-6)-pathways are central in cardiovascular disease. Knowledge of how the inflammasome influences the MVs is limited. In a cross-sectional study, we assessed whether MVs in plasma associate with genes...

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Bibliographic Details
Main Authors: Vibeke Bratseth, Jostein Nordeng, Ragnhild Helseth, Svein Solheim, Sissel Åkra, Harald Arnesen, Gemma Chiva-Blanch, Ingebjørg Seljeflot
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Biomedicines
Subjects:
microvesicles
NLRP3 inflammasome
IL-6 signalling pathway
ST-elevation myocardial infarction
Annexin V
immunothrombosis
Online Access:https://www.mdpi.com/2227-9059/10/9/2196

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