A case of Avelumab response to multiple bone and lymph node metastases of plasmacytoid variant bladder cancer
A 74-year-old man was diagnosed with bladder cancer and referred to our department. For definitive diagnosis, transurethral resection of the bladder tumor(TURBT) was performed. The pathological result showed plasmacytoid variant of urothelial carcinoma. Subsequently, robot-assisted radical cystectom...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-03-01
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| Series: | Urology Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S221444202300044X |
| _version_ | 1828011228873621504 |
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| author | Kazuki Kokura Jun Watanabe Takaaki Takuma Shoko Uketa Yuichi Uemura Masayuki Uegaki |
| author_facet | Kazuki Kokura Jun Watanabe Takaaki Takuma Shoko Uketa Yuichi Uemura Masayuki Uegaki |
| author_sort | Kazuki Kokura |
| collection | DOAJ |
| description | A 74-year-old man was diagnosed with bladder cancer and referred to our department. For definitive diagnosis, transurethral resection of the bladder tumor(TURBT) was performed. The pathological result showed plasmacytoid variant of urothelial carcinoma. Subsequently, robot-assisted radical cystectomy, lymph node dissection and ileal conduit was performed, but multiple bone metastases and periaortic lymph node metastases newly appeared 30 days later. Gemcitabine and cisplatin (GC) was started, and after 4 courses, the patient became Partial Response (PR), and was switched to Avelumab as maintenance therapy. After about 1 year of maintenance therapy, the patient is still in PR. |
| first_indexed | 2024-04-10T09:12:03Z |
| format | Article |
| id | doaj.art-5173bbfa80714df7ad31e85ec7fcc9e4 |
| institution | Directory Open Access Journal |
| issn | 2214-4420 |
| language | English |
| last_indexed | 2024-04-10T09:12:03Z |
| publishDate | 2023-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Urology Case Reports |
| spelling | doaj.art-5173bbfa80714df7ad31e85ec7fcc9e42023-02-21T05:09:24ZengElsevierUrology Case Reports2214-44202023-03-0147102358A case of Avelumab response to multiple bone and lymph node metastases of plasmacytoid variant bladder cancerKazuki Kokura0Jun Watanabe1Takaaki Takuma2Shoko Uketa3Yuichi Uemura4Masayuki Uegaki5Corresponding author. 1094 Tobera, Toyooka City, 668-8501 1094, Hyogo Prefecture, Japan.; Toyooka Hospital, 1094 Tobera, Toyooka City, Hyogo Prefecture, JapanToyooka Hospital, 1094 Tobera, Toyooka City, Hyogo Prefecture, JapanToyooka Hospital, 1094 Tobera, Toyooka City, Hyogo Prefecture, JapanToyooka Hospital, 1094 Tobera, Toyooka City, Hyogo Prefecture, JapanToyooka Hospital, 1094 Tobera, Toyooka City, Hyogo Prefecture, JapanToyooka Hospital, 1094 Tobera, Toyooka City, Hyogo Prefecture, JapanA 74-year-old man was diagnosed with bladder cancer and referred to our department. For definitive diagnosis, transurethral resection of the bladder tumor(TURBT) was performed. The pathological result showed plasmacytoid variant of urothelial carcinoma. Subsequently, robot-assisted radical cystectomy, lymph node dissection and ileal conduit was performed, but multiple bone metastases and periaortic lymph node metastases newly appeared 30 days later. Gemcitabine and cisplatin (GC) was started, and after 4 courses, the patient became Partial Response (PR), and was switched to Avelumab as maintenance therapy. After about 1 year of maintenance therapy, the patient is still in PR.http://www.sciencedirect.com/science/article/pii/S221444202300044XAvelumabPlasmacytoidBladder cancer |
| spellingShingle | Kazuki Kokura Jun Watanabe Takaaki Takuma Shoko Uketa Yuichi Uemura Masayuki Uegaki A case of Avelumab response to multiple bone and lymph node metastases of plasmacytoid variant bladder cancer Urology Case Reports Avelumab Plasmacytoid Bladder cancer |
| title | A case of Avelumab response to multiple bone and lymph node metastases of plasmacytoid variant bladder cancer |
| title_full | A case of Avelumab response to multiple bone and lymph node metastases of plasmacytoid variant bladder cancer |
| title_fullStr | A case of Avelumab response to multiple bone and lymph node metastases of plasmacytoid variant bladder cancer |
| title_full_unstemmed | A case of Avelumab response to multiple bone and lymph node metastases of plasmacytoid variant bladder cancer |
| title_short | A case of Avelumab response to multiple bone and lymph node metastases of plasmacytoid variant bladder cancer |
| title_sort | case of avelumab response to multiple bone and lymph node metastases of plasmacytoid variant bladder cancer |
| topic | Avelumab Plasmacytoid Bladder cancer |
| url | http://www.sciencedirect.com/science/article/pii/S221444202300044X |
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