Tim-3 facilitates immune escape in benzene-induced acute myeloid leukemia mouse model by promoting macrophage M2 polarization

Tim-3 facilitates immune escape in benzene-induced acute myeloid leukemia mouse model by promoting macrophage M2 polarization

Benzene poisoning can cause acute myeloid leukemia (AML) through a variety of passways. Tim-3 has gained prominence as a potential candidate in mediating immunosuppression in tumor microenvironments. The macrophage polarization is also related to immune escape. Herein, we reported that Tim-3 and mac...

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Bibliographic Details
Main Authors: Qiong Ning, Tianzi Jian, Siqi Cui, Longke Shi, Xiangdong Jian, Xiaopeng He, Xiangxing Zhang, Xiangxin Li
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Tim-3
Benzene
Acute myeloid leukemia
Macrophage polarization
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651323010369

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