Determination of estrogen receptor alpha gene (ESR1) polymorphism and its relation to systemic lupus erythematosus disease status

Determination of estrogen receptor alpha gene (ESR1) polymorphism and its relation to systemic lupus erythematosus disease status

Abstract Background Systemic lupus erythematosus (SLE) is a chronic inflammatory disease with variable clinical manifestations that can affect various organs and tissues. Estrogen is an important element that performs a vital role in the pathology of SLE. It acts on target cells through binding to e...

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Bibliographic Details
Main Authors: Samia M. Abdel-Monem, Abdel Wahab Sh. E. El-Brashy, Waleed A. Hassan, Omnia A. Abdullah, Dalia H. Almallah
Format: Article
Language:English
Published: SpringerOpen 2022-03-01
Series:Egyptian Rheumatology and Rehabilitation
Subjects:
Systemic lupus erythematosus
Estrogen receptors
Estrogen receptor alpha gene polymorphism
Systemic Lupus Erythematosus Activity Index
Online Access:https://doi.org/10.1186/s43166-022-00119-z

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