Home-cage behavior is impacted by stress exposure in rats
Being social animals, rats exhibit a range of social behaviors that help them build social bonds and maintain group cohesion. Behavior is influenced by multiple factors, including stress exposure, and the expression of the impact of stress on both social and non-social behaviors may also be affected...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-06-01
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| Series: | Frontiers in Behavioral Neuroscience |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fnbeh.2023.1195011/full |
| _version_ | 1797808327431815168 |
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| author | Evren Eraslan Evren Eraslan Evren Eraslan Magda João Castelhano-Carlos Magda João Castelhano-Carlos Liliana Amorim Liliana Amorim Liliana Amorim Carina Soares-Cunha Carina Soares-Cunha Ana João Rodrigues Ana João Rodrigues Nuno Sousa Nuno Sousa Nuno Sousa Nuno Sousa |
| author_facet | Evren Eraslan Evren Eraslan Evren Eraslan Magda João Castelhano-Carlos Magda João Castelhano-Carlos Liliana Amorim Liliana Amorim Liliana Amorim Carina Soares-Cunha Carina Soares-Cunha Ana João Rodrigues Ana João Rodrigues Nuno Sousa Nuno Sousa Nuno Sousa Nuno Sousa |
| author_sort | Evren Eraslan |
| collection | DOAJ |
| description | Being social animals, rats exhibit a range of social behaviors that help them build social bonds and maintain group cohesion. Behavior is influenced by multiple factors, including stress exposure, and the expression of the impact of stress on both social and non-social behaviors may also be affected by the living conditions of rats. In this study, we explored the physiological and behavioral effects of chronic unpredictable stress on group-housed rats in the PhenoWorld (PhW), a socially and physically enriched environment closer to real-life conditions. Two independent experiments were performed: one in the control condition (PhW control, n = 8) and one in the stress condition (PhW stress, n = 8). Control animals remained undisturbed except for cage cleaning and daily handling procedures. Stress group animals were all exposed to chronic unpredictable stress. Data confirm that stress exposure triggers anxiety-like behavior in the PhW. In terms of home-cage behaviors, we found that stress affects social behaviors (by decreased playing and increased huddling behaviors) and non-social behaviors (as shown by the decrease in rearing and walking behaviors). These results are of relevance to expand our knowledge on the influence of stress on social and non-social behaviors, which are of importance to understand better species-typical behaviors. |
| first_indexed | 2024-03-13T06:35:54Z |
| format | Article |
| id | doaj.art-517d096a98a64762b996aa5e3982160c |
| institution | Directory Open Access Journal |
| issn | 1662-5153 |
| language | English |
| last_indexed | 2024-03-13T06:35:54Z |
| publishDate | 2023-06-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Behavioral Neuroscience |
| spelling | doaj.art-517d096a98a64762b996aa5e3982160c2023-06-09T04:31:02ZengFrontiers Media S.A.Frontiers in Behavioral Neuroscience1662-51532023-06-011710.3389/fnbeh.2023.11950111195011Home-cage behavior is impacted by stress exposure in ratsEvren Eraslan0Evren Eraslan1Evren Eraslan2Magda João Castelhano-Carlos3Magda João Castelhano-Carlos4Liliana Amorim5Liliana Amorim6Liliana Amorim7Carina Soares-Cunha8Carina Soares-Cunha9Ana João Rodrigues10Ana João Rodrigues11Nuno Sousa12Nuno Sousa13Nuno Sousa14Nuno Sousa15School of Medicine, Life and Health Sciences Research Institute (ICVS), University of Minho, Braga, PortugalICVS/3B's – PT Government Associate Laboratory, Guimarães, PortugalDepartment of Physiology, Faculty of Veterinary Medicine, Istanbul University-Cerrahpasa, Istanbul, TürkiyeSchool of Medicine, Life and Health Sciences Research Institute (ICVS), University of Minho, Braga, PortugalICVS/3B's – PT Government Associate Laboratory, Guimarães, PortugalSchool of Medicine, Life and Health Sciences Research Institute (ICVS), University of Minho, Braga, PortugalICVS/3B's – PT Government Associate Laboratory, Guimarães, PortugalP5 Clinical Digital Center, Braga, PortugalSchool of Medicine, Life and Health Sciences Research Institute (ICVS), University of Minho, Braga, PortugalICVS/3B's – PT Government Associate Laboratory, Guimarães, PortugalSchool of Medicine, Life and Health Sciences Research Institute (ICVS), University of Minho, Braga, PortugalICVS/3B's – PT Government Associate Laboratory, Guimarães, PortugalSchool of Medicine, Life and Health Sciences Research Institute (ICVS), University of Minho, Braga, PortugalICVS/3B's – PT Government Associate Laboratory, Guimarães, PortugalP5 Clinical Digital Center, Braga, PortugalClinical Academic Center (2CA), Braga, PortugalBeing social animals, rats exhibit a range of social behaviors that help them build social bonds and maintain group cohesion. Behavior is influenced by multiple factors, including stress exposure, and the expression of the impact of stress on both social and non-social behaviors may also be affected by the living conditions of rats. In this study, we explored the physiological and behavioral effects of chronic unpredictable stress on group-housed rats in the PhenoWorld (PhW), a socially and physically enriched environment closer to real-life conditions. Two independent experiments were performed: one in the control condition (PhW control, n = 8) and one in the stress condition (PhW stress, n = 8). Control animals remained undisturbed except for cage cleaning and daily handling procedures. Stress group animals were all exposed to chronic unpredictable stress. Data confirm that stress exposure triggers anxiety-like behavior in the PhW. In terms of home-cage behaviors, we found that stress affects social behaviors (by decreased playing and increased huddling behaviors) and non-social behaviors (as shown by the decrease in rearing and walking behaviors). These results are of relevance to expand our knowledge on the influence of stress on social and non-social behaviors, which are of importance to understand better species-typical behaviors.https://www.frontiersin.org/articles/10.3389/fnbeh.2023.1195011/fullsocial behaviorratsstressCUSenriched environmenthome-cage behavior |
| spellingShingle | Evren Eraslan Evren Eraslan Evren Eraslan Magda João Castelhano-Carlos Magda João Castelhano-Carlos Liliana Amorim Liliana Amorim Liliana Amorim Carina Soares-Cunha Carina Soares-Cunha Ana João Rodrigues Ana João Rodrigues Nuno Sousa Nuno Sousa Nuno Sousa Nuno Sousa Home-cage behavior is impacted by stress exposure in rats Frontiers in Behavioral Neuroscience social behavior rats stress CUS enriched environment home-cage behavior |
| title | Home-cage behavior is impacted by stress exposure in rats |
| title_full | Home-cage behavior is impacted by stress exposure in rats |
| title_fullStr | Home-cage behavior is impacted by stress exposure in rats |
| title_full_unstemmed | Home-cage behavior is impacted by stress exposure in rats |
| title_short | Home-cage behavior is impacted by stress exposure in rats |
| title_sort | home cage behavior is impacted by stress exposure in rats |
| topic | social behavior rats stress CUS enriched environment home-cage behavior |
| url | https://www.frontiersin.org/articles/10.3389/fnbeh.2023.1195011/full |
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