Polyrhodanine-based nanomaterials for biomedical applications: A review
Rhodanine is a heterocyclic organic compound that has been investigated for its potential biomedical applications, particularly in drug discovery. Rhodanine derivatives have been examined as the medication options for numerous illnesses, including cancer, inflammation, and infectious diseases. Some...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2024-04-01
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| Series: | Heliyon |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844024049338 |
| _version_ | 1797214888433549312 |
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| author | Ibrahim Huzyan Hiba Jin Kwei Koh Chin Wei Lai Seyyed Mojtaba Mousavi Irfan Anjum Badruddin Mohamed Hussien Jest Phia Wong |
| author_facet | Ibrahim Huzyan Hiba Jin Kwei Koh Chin Wei Lai Seyyed Mojtaba Mousavi Irfan Anjum Badruddin Mohamed Hussien Jest Phia Wong |
| author_sort | Ibrahim Huzyan Hiba |
| collection | DOAJ |
| description | Rhodanine is a heterocyclic organic compound that has been investigated for its potential biomedical applications, particularly in drug discovery. Rhodanine derivatives have been examined as the medication options for numerous illnesses, including cancer, inflammation, and infectious diseases. Some rhodanine derivatives have also shown promising activity against drug-resistant strains of bacteria and viruses. One of these derivatives is polyrhodanine (PR), a conducting polymer that has gained attention for its biomedical properties. This review article summarises the latest advancements in creating biomaterials based on PR for biosensing, antimicrobial treatments, and anticancer therapies. The distinctive characteristics of PR, such as biocompatibility, biodegradability, and good conductivity, render it an attractive candidate for these applications. The article also explores obstacles and potential future paths for advancing biomaterials made with PR, including synthesis modifications, characterisation techniques, and in vivo evaluation of biocompatibility and efficacy. Overall, as an emerging research topic, this review emphasises the potential of PR as a promising biomaterial for various biomedical applications and provides insights into the contemporary state of research and prospective directions for investigation. |
| first_indexed | 2024-04-24T11:21:20Z |
| format | Article |
| id | doaj.art-517d33f5112944bc941955d419b456da |
| institution | Directory Open Access Journal |
| issn | 2405-8440 |
| language | English |
| last_indexed | 2024-04-24T11:21:20Z |
| publishDate | 2024-04-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Heliyon |
| spelling | doaj.art-517d33f5112944bc941955d419b456da2024-04-11T04:41:34ZengElsevierHeliyon2405-84402024-04-01107e28902Polyrhodanine-based nanomaterials for biomedical applications: A reviewIbrahim Huzyan Hiba0Jin Kwei Koh1Chin Wei Lai2Seyyed Mojtaba Mousavi3Irfan Anjum Badruddin4Mohamed Hussien5Jest Phia Wong6Nanotechnology and Catalysis Research Centre (NANOCAT), Institute for Advanced Studies (IAS), University of Malaya (UM), 50603, Kuala Lumpur, MalaysiaNanotechnology and Catalysis Research Centre (NANOCAT), Institute for Advanced Studies (IAS), University of Malaya (UM), 50603, Kuala Lumpur, MalaysiaNanotechnology and Catalysis Research Centre (NANOCAT), Institute for Advanced Studies (IAS), University of Malaya (UM), 50603, Kuala Lumpur, Malaysia; Corresponding author.Department of Chemical Engineering, National Taiwan University of Science and Technology, TaiwanMechanical Engineering Department, College of Engineering, King Khalid University, Abha, 61421, Saudi ArabiaDepartment of Chemistry, Faculty of Science, King Khalid University, P.O. Box 9004, Abha, 61413, Saudi ArabiaHarper Elite Sdn Bhd, UG-23, PJ Midtown, Jalan Kemajuan, Seksyen 13, 46200, Petaling Jaya, Selangor Darul Ehsan, MalaysiaRhodanine is a heterocyclic organic compound that has been investigated for its potential biomedical applications, particularly in drug discovery. Rhodanine derivatives have been examined as the medication options for numerous illnesses, including cancer, inflammation, and infectious diseases. Some rhodanine derivatives have also shown promising activity against drug-resistant strains of bacteria and viruses. One of these derivatives is polyrhodanine (PR), a conducting polymer that has gained attention for its biomedical properties. This review article summarises the latest advancements in creating biomaterials based on PR for biosensing, antimicrobial treatments, and anticancer therapies. The distinctive characteristics of PR, such as biocompatibility, biodegradability, and good conductivity, render it an attractive candidate for these applications. The article also explores obstacles and potential future paths for advancing biomaterials made with PR, including synthesis modifications, characterisation techniques, and in vivo evaluation of biocompatibility and efficacy. Overall, as an emerging research topic, this review emphasises the potential of PR as a promising biomaterial for various biomedical applications and provides insights into the contemporary state of research and prospective directions for investigation.http://www.sciencedirect.com/science/article/pii/S2405844024049338 |
| spellingShingle | Ibrahim Huzyan Hiba Jin Kwei Koh Chin Wei Lai Seyyed Mojtaba Mousavi Irfan Anjum Badruddin Mohamed Hussien Jest Phia Wong Polyrhodanine-based nanomaterials for biomedical applications: A review Heliyon |
| title | Polyrhodanine-based nanomaterials for biomedical applications: A review |
| title_full | Polyrhodanine-based nanomaterials for biomedical applications: A review |
| title_fullStr | Polyrhodanine-based nanomaterials for biomedical applications: A review |
| title_full_unstemmed | Polyrhodanine-based nanomaterials for biomedical applications: A review |
| title_short | Polyrhodanine-based nanomaterials for biomedical applications: A review |
| title_sort | polyrhodanine based nanomaterials for biomedical applications a review |
| url | http://www.sciencedirect.com/science/article/pii/S2405844024049338 |
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