Salmonella enterica Serotype Typhi with Nonclassical Quinolone Resistance Phenotype

We report Salmonella enterica serotype Typhi strains with a nonclassical quinolone resistance phenotype (i.e., decreased susceptibility to ciprofloxacin but with susceptibility to nalidixic acid) associated with a nonsynonymous mutation at codon 464 of the gyrB gene. These strains, not detected by t...

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Main Authors: Marie Accou-Demartin, Valérie Gaborieau, Yajun Song, Philippe Roumagnac, Bruno Marchou, Mark Achtman, François-Xavier Weill
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2011-06-01
Series:Emerging Infectious Diseases
Subjects:
Online Access:https://wwwnc.cdc.gov/eid/article/17/6/10-1242_article
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author Marie Accou-Demartin
Valérie Gaborieau
Yajun Song
Philippe Roumagnac
Bruno Marchou
Mark Achtman
François-Xavier Weill
author_facet Marie Accou-Demartin
Valérie Gaborieau
Yajun Song
Philippe Roumagnac
Bruno Marchou
Mark Achtman
François-Xavier Weill
author_sort Marie Accou-Demartin
collection DOAJ
description We report Salmonella enterica serotype Typhi strains with a nonclassical quinolone resistance phenotype (i.e., decreased susceptibility to ciprofloxacin but with susceptibility to nalidixic acid) associated with a nonsynonymous mutation at codon 464 of the gyrB gene. These strains, not detected by the nalidixic acid disk screening test, can result in fluoroquinolone treatment failure.
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spelling doaj.art-517d4fc558634729874ab70e8d6d3a2f2022-12-21T18:38:24ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592011-06-011761091109410.3201/eid1706.101242Salmonella enterica Serotype Typhi with Nonclassical Quinolone Resistance PhenotypeMarie Accou-DemartinValérie GaborieauYajun SongPhilippe RoumagnacBruno MarchouMark AchtmanFrançois-Xavier WeillWe report Salmonella enterica serotype Typhi strains with a nonclassical quinolone resistance phenotype (i.e., decreased susceptibility to ciprofloxacin but with susceptibility to nalidixic acid) associated with a nonsynonymous mutation at codon 464 of the gyrB gene. These strains, not detected by the nalidixic acid disk screening test, can result in fluoroquinolone treatment failure.https://wwwnc.cdc.gov/eid/article/17/6/10-1242_articleSalmonellatyphoid feverciprofloxacintreatment failuregyrBbacteria
spellingShingle Marie Accou-Demartin
Valérie Gaborieau
Yajun Song
Philippe Roumagnac
Bruno Marchou
Mark Achtman
François-Xavier Weill
Salmonella enterica Serotype Typhi with Nonclassical Quinolone Resistance Phenotype
Emerging Infectious Diseases
Salmonella
typhoid fever
ciprofloxacin
treatment failure
gyrB
bacteria
title Salmonella enterica Serotype Typhi with Nonclassical Quinolone Resistance Phenotype
title_full Salmonella enterica Serotype Typhi with Nonclassical Quinolone Resistance Phenotype
title_fullStr Salmonella enterica Serotype Typhi with Nonclassical Quinolone Resistance Phenotype
title_full_unstemmed Salmonella enterica Serotype Typhi with Nonclassical Quinolone Resistance Phenotype
title_short Salmonella enterica Serotype Typhi with Nonclassical Quinolone Resistance Phenotype
title_sort salmonella enterica serotype typhi with nonclassical quinolone resistance phenotype
topic Salmonella
typhoid fever
ciprofloxacin
treatment failure
gyrB
bacteria
url https://wwwnc.cdc.gov/eid/article/17/6/10-1242_article
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