Depression, anxiety, insomnia and interleukins in the early postpartum period
BackgroundSome new mothers have been shown to suffer from anxiety and depression associated with insomnia during the postpartum period. Our study assessed the impact of demographic, psychopathological, and biochemical factors on the incidence of depression in women during the early postpartum period...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-09-01
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| Series: | Frontiers in Psychiatry |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fpsyt.2023.1266390/full |
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| author | Ewa Drozdowicz-Jastrzębska Anna Mach Michał Skalski Piotr Januszko Zoulikha Jabiry-Zieniewicz Marcin Siwek Zbigniew Maciej Wawrzyniak Maria Radziwoń-Zaleska |
| author_facet | Ewa Drozdowicz-Jastrzębska Anna Mach Michał Skalski Piotr Januszko Zoulikha Jabiry-Zieniewicz Marcin Siwek Zbigniew Maciej Wawrzyniak Maria Radziwoń-Zaleska |
| author_sort | Ewa Drozdowicz-Jastrzębska |
| collection | DOAJ |
| description | BackgroundSome new mothers have been shown to suffer from anxiety and depression associated with insomnia during the postpartum period. Our study assessed the impact of demographic, psychopathological, and biochemical factors on the incidence of depression in women during the early postpartum period.MethodsA total of 119 women were evaluated at 24–48 h postpartum with the following psychometric scales: Hamilton Depression Rating Scale (HDRS), Edinburgh Postnatal Depression Scale (EPDS), Hamilton Anxiety Rating Scale (HARS) and Athens Insomnia Scale (AIS). In addition, blood was drawn to assay interleukin 6 (IL-6) and interleukin 10 (IL-10).ResultsThe factors that had the greatest impact on the risk of postpartum depression detected with the HDRS were high HARS scores and evidence of insomnia in the AIS. There were no significant differences in IL-6 or IL-10 levels in women with and without depression (based on either HDRS or EPDS scores) and insomnia (based on AIS) after childbirth. Considering demographic factors, divorced and single women were shown to be at higher risk of postpartum depression (based on EPDS scores).LimitationsSmall sample size and short observation span.ConclusionThis study highlights the relationship between postpartum depression and both anxiety and insomnia and emphasises the importance to assess symptoms of anxiety and sleep quality as part of screening in women at risk of postpartum depression. |
| first_indexed | 2024-03-11T21:14:50Z |
| format | Article |
| id | doaj.art-5181f709e8f1422489d07549a2805856 |
| institution | Directory Open Access Journal |
| issn | 1664-0640 |
| language | English |
| last_indexed | 2024-03-11T21:14:50Z |
| publishDate | 2023-09-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Psychiatry |
| spelling | doaj.art-5181f709e8f1422489d07549a28058562023-09-29T05:08:30ZengFrontiers Media S.A.Frontiers in Psychiatry1664-06402023-09-011410.3389/fpsyt.2023.12663901266390Depression, anxiety, insomnia and interleukins in the early postpartum periodEwa Drozdowicz-Jastrzębska0Anna Mach1Michał Skalski2Piotr Januszko3Zoulikha Jabiry-Zieniewicz4Marcin Siwek5Zbigniew Maciej Wawrzyniak6Maria Radziwoń-Zaleska7Department of Psychiatry, Medical University of Warsaw, Warsaw, PolandDepartment of Psychiatry, Medical University of Warsaw, Warsaw, PolandDepartment of Psychiatry, Medical University of Warsaw, Warsaw, PolandDepartment of Psychiatry, Medical University of Warsaw, Warsaw, Poland1st Department of Obstetrics and Gynecology, Medical University of Warsaw, Warsaw, PolandDepartment of Affective Disorders, Jagiellonian University Medical College, Cracow, PolandFaculty of Electronics and Information Technology, Warsaw University of Technology, Warsaw, PolandDepartment of Psychiatry, Medical University of Warsaw, Warsaw, PolandBackgroundSome new mothers have been shown to suffer from anxiety and depression associated with insomnia during the postpartum period. Our study assessed the impact of demographic, psychopathological, and biochemical factors on the incidence of depression in women during the early postpartum period.MethodsA total of 119 women were evaluated at 24–48 h postpartum with the following psychometric scales: Hamilton Depression Rating Scale (HDRS), Edinburgh Postnatal Depression Scale (EPDS), Hamilton Anxiety Rating Scale (HARS) and Athens Insomnia Scale (AIS). In addition, blood was drawn to assay interleukin 6 (IL-6) and interleukin 10 (IL-10).ResultsThe factors that had the greatest impact on the risk of postpartum depression detected with the HDRS were high HARS scores and evidence of insomnia in the AIS. There were no significant differences in IL-6 or IL-10 levels in women with and without depression (based on either HDRS or EPDS scores) and insomnia (based on AIS) after childbirth. Considering demographic factors, divorced and single women were shown to be at higher risk of postpartum depression (based on EPDS scores).LimitationsSmall sample size and short observation span.ConclusionThis study highlights the relationship between postpartum depression and both anxiety and insomnia and emphasises the importance to assess symptoms of anxiety and sleep quality as part of screening in women at risk of postpartum depression.https://www.frontiersin.org/articles/10.3389/fpsyt.2023.1266390/fulldepressionanxietyinsomniainterleukinspostpartum period |
| spellingShingle | Ewa Drozdowicz-Jastrzębska Anna Mach Michał Skalski Piotr Januszko Zoulikha Jabiry-Zieniewicz Marcin Siwek Zbigniew Maciej Wawrzyniak Maria Radziwoń-Zaleska Depression, anxiety, insomnia and interleukins in the early postpartum period Frontiers in Psychiatry depression anxiety insomnia interleukins postpartum period |
| title | Depression, anxiety, insomnia and interleukins in the early postpartum period |
| title_full | Depression, anxiety, insomnia and interleukins in the early postpartum period |
| title_fullStr | Depression, anxiety, insomnia and interleukins in the early postpartum period |
| title_full_unstemmed | Depression, anxiety, insomnia and interleukins in the early postpartum period |
| title_short | Depression, anxiety, insomnia and interleukins in the early postpartum period |
| title_sort | depression anxiety insomnia and interleukins in the early postpartum period |
| topic | depression anxiety insomnia interleukins postpartum period |
| url | https://www.frontiersin.org/articles/10.3389/fpsyt.2023.1266390/full |
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