Discovery of a Novel Coronavirus in Swedish Bank Voles (<i>Myodes glareolus</i>)
The unprecedented pandemic COVID-19, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), with bats as original reservoirs, has once again highlighted the importance of exploring the interface of wildlife diseases and human health. In this study, we identified a novel <i>Bet...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-06-01
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| Series: | Viruses |
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| Online Access: | https://www.mdpi.com/1999-4915/14/6/1205 |
| _version_ | 1797481413518295040 |
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| author | Anishia Wasberg Jayna Raghwani Jinlin Li John H.-O. Pettersson Johanna F. Lindahl Åke Lundkvist Jiaxin Ling |
| author_facet | Anishia Wasberg Jayna Raghwani Jinlin Li John H.-O. Pettersson Johanna F. Lindahl Åke Lundkvist Jiaxin Ling |
| author_sort | Anishia Wasberg |
| collection | DOAJ |
| description | The unprecedented pandemic COVID-19, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), with bats as original reservoirs, has once again highlighted the importance of exploring the interface of wildlife diseases and human health. In this study, we identified a novel <i>Betacoronavirus</i> from bank voles (<i>Myodes glareolus</i>) in Grimsö, Sweden, and this virus is designated as Grimso virus. Repeated detection over three years and an overall prevalence of 3.4% suggest that the virus commonly occurs in bank voles. Furthermore, phylogenetic analyses indicate that the Grimso virus belongs to a highly divergent <i>Embecovirus</i> lineage predominantly associated with bank voles. Given that bank voles are one of the most common rodent species in Sweden and Europe, our findings indicate that Grimso virus might be circulating widely in bank voles and further point out the importance of sentinel surveillance of coronaviruses in wild small mammalian animals, especially in wild rodents. |
| first_indexed | 2024-03-09T22:14:13Z |
| format | Article |
| id | doaj.art-518366dc66d44c649de623100034a891 |
| institution | Directory Open Access Journal |
| issn | 1999-4915 |
| language | English |
| last_indexed | 2024-03-09T22:14:13Z |
| publishDate | 2022-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Viruses |
| spelling | doaj.art-518366dc66d44c649de623100034a8912023-11-23T19:25:24ZengMDPI AGViruses1999-49152022-06-01146120510.3390/v14061205Discovery of a Novel Coronavirus in Swedish Bank Voles (<i>Myodes glareolus</i>)Anishia Wasberg0Jayna Raghwani1Jinlin Li2John H.-O. Pettersson3Johanna F. Lindahl4Åke Lundkvist5Jiaxin Ling6Zoonosis Science Center, Department of Medical Biochemistry and Microbiology, Uppsala University, 751 23 Uppsala, SwedenDepartment of Zoology, University of Oxford, Oxford OX1 4BH, UKDepartment of Medical Biochemistry and Microbiology, Uppsala University, 751 23 Uppsala, SwedenZoonosis Science Center, Department of Medical Biochemistry and Microbiology, Uppsala University, 751 23 Uppsala, SwedenZoonosis Science Center, Department of Medical Biochemistry and Microbiology, Uppsala University, 751 23 Uppsala, SwedenZoonosis Science Center, Department of Medical Biochemistry and Microbiology, Uppsala University, 751 23 Uppsala, SwedenZoonosis Science Center, Department of Medical Biochemistry and Microbiology, Uppsala University, 751 23 Uppsala, SwedenThe unprecedented pandemic COVID-19, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), with bats as original reservoirs, has once again highlighted the importance of exploring the interface of wildlife diseases and human health. In this study, we identified a novel <i>Betacoronavirus</i> from bank voles (<i>Myodes glareolus</i>) in Grimsö, Sweden, and this virus is designated as Grimso virus. Repeated detection over three years and an overall prevalence of 3.4% suggest that the virus commonly occurs in bank voles. Furthermore, phylogenetic analyses indicate that the Grimso virus belongs to a highly divergent <i>Embecovirus</i> lineage predominantly associated with bank voles. Given that bank voles are one of the most common rodent species in Sweden and Europe, our findings indicate that Grimso virus might be circulating widely in bank voles and further point out the importance of sentinel surveillance of coronaviruses in wild small mammalian animals, especially in wild rodents.https://www.mdpi.com/1999-4915/14/6/1205coronavirusbank volesRNA-sequencingprevalence |
| spellingShingle | Anishia Wasberg Jayna Raghwani Jinlin Li John H.-O. Pettersson Johanna F. Lindahl Åke Lundkvist Jiaxin Ling Discovery of a Novel Coronavirus in Swedish Bank Voles (<i>Myodes glareolus</i>) Viruses coronavirus bank voles RNA-sequencing prevalence |
| title | Discovery of a Novel Coronavirus in Swedish Bank Voles (<i>Myodes glareolus</i>) |
| title_full | Discovery of a Novel Coronavirus in Swedish Bank Voles (<i>Myodes glareolus</i>) |
| title_fullStr | Discovery of a Novel Coronavirus in Swedish Bank Voles (<i>Myodes glareolus</i>) |
| title_full_unstemmed | Discovery of a Novel Coronavirus in Swedish Bank Voles (<i>Myodes glareolus</i>) |
| title_short | Discovery of a Novel Coronavirus in Swedish Bank Voles (<i>Myodes glareolus</i>) |
| title_sort | discovery of a novel coronavirus in swedish bank voles i myodes glareolus i |
| topic | coronavirus bank voles RNA-sequencing prevalence |
| url | https://www.mdpi.com/1999-4915/14/6/1205 |
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