Loss of a Branch Sugar in the Acinetobacter baumannii K3-Type Capsular Polysaccharide Due To Frameshifts in the gtr6 Glycosyltransferase Gene Leads To Susceptibility To Phage APK37.1

Loss of a Branch Sugar in the Acinetobacter baumannii K3-Type Capsular Polysaccharide Due To Frameshifts in the gtr6 Glycosyltransferase Gene Leads To Susceptibility To Phage APK37.1

ABSTRACT The type of capsular polysaccharide (CPS) on the cell surface of Acinetobacter baumannii can determine the specificity of lytic bacteriophage under consideration for therapeutic use. Here, we report the isolation of a phage on an extensively antibiotic resistant ST2 A. baumannii isolate AB5...

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Bibliographic Details
Main Authors: Olga Y. Timoshina, Anastasiya A. Kasimova, Mikhail M. Shneider, Nikolay P. Arbatsky, Alexander S. Shashkov, Andrey A. Shelenkov, Yuliya V. Mikhailova, Anastasiya V. Popova, Ruth M. Hall, Yuriy A. Knirel, Johanna J. Kenyon
Format: Article
Language:English
Published: American Society for Microbiology 2023-02-01
Series:Microbiology Spectrum
Subjects:
Acinetobacter baumannii
capsular polysaccharide
K locus
KL3
K3-v1
APK37.1
Online Access:https://journals.asm.org/doi/10.1128/spectrum.03631-22

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