A Clinical Trial of The Evaluation of Environmental Exposure in Yttrium 90 Radioembolization

Aim: The aim of this study is to measure the dose rate of twodifferent forms of Y-90 microsphere used for radioembolization and to evaluatethe results according to radiation safety regularities. Material and Methods:19 patients were enrolled in study (Age:61±1.5, F/M:12/7). As a result of theevaluat...

Full description

Bibliographic Details
Main Authors: Handan Tanyildizi, İffet Çavdar, Mustafa Demir
Format: Article
Language:English
Published: Sakarya University 2018-12-01
Series:Sakarya Üniversitesi Fen Bilimleri Enstitüsü Dergisi
Subjects:
Online Access:https://dergipark.org.tr/tr/download/article-file/547444
Description
Summary:Aim: The aim of this study is to measure the dose rate of twodifferent forms of Y-90 microsphere used for radioembolization and to evaluatethe results according to radiation safety regularities. Material and Methods:19 patients were enrolled in study (Age:61±1.5, F/M:12/7). As a result of theevaluation of the physicians, 7 patients were treated with TheraSphere and 12patients were treated with SIR-Sphere. Dose rate measurements were taken at thestage of activity preparation, injection, radioactive wastes and discharge ofpatients via electronic dosimeter (ED). Results: The staff was exposed to doserate of 1,3.10-4 μSv/MBq.h during activity preparation stage, 2,4.10-4 μSv/MBq.h in injectionstage for Therapshere application. For SIR-spheres application, the staff wasexposed to dose rate of 24,5.10-4 μSv/MBq.h during activity preparationstage, 10,1.10-4 μSv/MBq.h in injection stage. The average amount ofdose received per operation was calculated 0.92±0.48 μSv in TheraSphere and3.22±0.89 μSv in SIR-Spheres. For discharge of the patients, the average doserate recorded from 1 m was found 4±0.28 μGy.h-1 for TheraSphere and3.2±0.15 μGy.h-1 for SIR-Spheres. The dose rate of radioactivewastes measured from the surface of the container which contained theradioactive wastes generated after the application was 0.5±0.1 μSv.h-1for TheraSphere and 1.1±0.08 μSv.h-1 for SIR-Spheres. Conclusion: Itis emphasized that Y-90 Therasphere application provides radiation safety morethan SIR-Spheres because of its closed system, even so both applications showslow dose rate around the patient and short-term storage of radioactive wastesafter application would be sufficient.
ISSN:2147-835X