| Summary: | Purpose: To report a case of chronic endophthalmitis caused by Aquamicrobium lusatiense following phacoemulsification surgery. Observations: A 71 year-old woman was referred for chronic ocular inflammation after cataract surgery. Serologic testing was negative for common infectious etiologies. Her condition deteriorated on immune-modulating therapy prompting vitreous biopsy, which confirmed infection with A. lusatiense. She was managed successfully with intravitreal antibiotic pharmacotherapy and intraocular lens explantation. Conclusion and Importance: This is the first reported case of A. lusatiense causing endophthalmitis, or disease in a human, in the literature.
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