Multidimensional Frailty and Vaccinations in Older People: A Cross-Sectional Study
It is known that influenza, herpes zoster, pneumococcal and pertussis infections may increase morbidity and mortality in older people. Vaccinations against these pathogens are effective in older adults. Frailty seems to be an important determinant of vaccination rates, yet data supporting this assoc...
| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-04-01
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| Series: | Vaccines |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2076-393X/10/4/555 |
| _version_ | 1797409044219035648 |
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| author | Nicola Veronese Giusy Vassallo Maria Armata Laura Cilona Salvatore Casalicchio Roberta Masnata Claudio Costantino Francesco Vitale Giovanni Maurizio Giammanco Stefania Maggi Shaun Sabico Nasser M. Al-Daghri Ligia J. Dominguez Mario Barbagallo |
| author_facet | Nicola Veronese Giusy Vassallo Maria Armata Laura Cilona Salvatore Casalicchio Roberta Masnata Claudio Costantino Francesco Vitale Giovanni Maurizio Giammanco Stefania Maggi Shaun Sabico Nasser M. Al-Daghri Ligia J. Dominguez Mario Barbagallo |
| author_sort | Nicola Veronese |
| collection | DOAJ |
| description | It is known that influenza, herpes zoster, pneumococcal and pertussis infections may increase morbidity and mortality in older people. Vaccinations against these pathogens are effective in older adults. Frailty seems to be an important determinant of vaccination rates, yet data supporting this association are still missing. Therefore, we aimed to investigate the prevalence of four recommended vaccinations (influenza, herpes zoster, pneumococcal and diphtheria-tetanus-pertussis) and the association with multidimensional frailty assessed using a self-reported comprehensive geriatric assessment tool, i.e., the multidimensional prognostic index (SELFY-MPI). Older participants visiting the outpatient clinic of Azienda Ospedaliera Universitaria, Palermo, Italy were included. The SELFY-MPI questionnaire score was calculated based on eight different domains, while the vaccination status was determined using self-reported information. We included 319 participants from the 500 initially considered (63.8%). Vaccination against influenza was observed in 70.5% of the cases, whilst only 1.3% received the vaccination against diphtheria-tetanus-pertussis. Participants with higher SELFY-MPI scores were more likely to report vaccination against pneumococcus (45.6 vs. 28.3%, <i>p</i> = 0.01), whilst no significant differences were observed for the other vaccinations. In conclusion, the coverage of recommended vaccinations is low. Higher SELFY-MPI scores and vaccination status, particularly anti-pneumococcus, appear to be associated, but future studies are urgently needed for confirming that frailty is associated with vaccination status in older people. |
| first_indexed | 2024-03-09T04:08:36Z |
| format | Article |
| id | doaj.art-5189a269d4b743edb7ca498c865fb08d |
| institution | Directory Open Access Journal |
| issn | 2076-393X |
| language | English |
| last_indexed | 2024-03-09T04:08:36Z |
| publishDate | 2022-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Vaccines |
| spelling | doaj.art-5189a269d4b743edb7ca498c865fb08d2023-12-03T14:03:31ZengMDPI AGVaccines2076-393X2022-04-0110455510.3390/vaccines10040555Multidimensional Frailty and Vaccinations in Older People: A Cross-Sectional StudyNicola Veronese0Giusy Vassallo1Maria Armata2Laura Cilona3Salvatore Casalicchio4Roberta Masnata5Claudio Costantino6Francesco Vitale7Giovanni Maurizio Giammanco8Stefania Maggi9Shaun Sabico10Nasser M. Al-Daghri11Ligia J. Dominguez12Mario Barbagallo13Geriatric Unit, Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties “G. D’Alessandro”, University of Palermo, 90127 Palermo, ItalyGeriatric Unit, Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties “G. D’Alessandro”, University of Palermo, 90127 Palermo, ItalyGeriatric Unit, Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties “G. D’Alessandro”, University of Palermo, 90127 Palermo, ItalyGeriatric Unit, Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties “G. D’Alessandro”, University of Palermo, 90127 Palermo, ItalyGeriatric Unit, Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties “G. D’Alessandro”, University of Palermo, 90127 Palermo, ItalyGeriatric Unit, Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties “G. D’Alessandro”, University of Palermo, 90127 Palermo, ItalyHygiene Section, Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties “G. D’Alessandro”, University of Palermo, 90127 Palermo, ItalyHygiene Section, Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties “G. D’Alessandro”, University of Palermo, 90127 Palermo, ItalyMicrobiology Section, Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties “G. D’Alessandro”, University of Palermo, 90127 Palermo, ItalyConsiglio Nazionale delle Ricerche, Neuroscience Institute, 35128 Padova, ItalyChair for Biomarkers of Chronic Diseases, Biochemistry Department, College of Science, King Saud University, Riyadh 11451, Saudi ArabiaChair for Biomarkers of Chronic Diseases, Biochemistry Department, College of Science, King Saud University, Riyadh 11451, Saudi ArabiaGeriatric Unit, Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties “G. D’Alessandro”, University of Palermo, 90127 Palermo, ItalyGeriatric Unit, Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties “G. D’Alessandro”, University of Palermo, 90127 Palermo, ItalyIt is known that influenza, herpes zoster, pneumococcal and pertussis infections may increase morbidity and mortality in older people. Vaccinations against these pathogens are effective in older adults. Frailty seems to be an important determinant of vaccination rates, yet data supporting this association are still missing. Therefore, we aimed to investigate the prevalence of four recommended vaccinations (influenza, herpes zoster, pneumococcal and diphtheria-tetanus-pertussis) and the association with multidimensional frailty assessed using a self-reported comprehensive geriatric assessment tool, i.e., the multidimensional prognostic index (SELFY-MPI). Older participants visiting the outpatient clinic of Azienda Ospedaliera Universitaria, Palermo, Italy were included. The SELFY-MPI questionnaire score was calculated based on eight different domains, while the vaccination status was determined using self-reported information. We included 319 participants from the 500 initially considered (63.8%). Vaccination against influenza was observed in 70.5% of the cases, whilst only 1.3% received the vaccination against diphtheria-tetanus-pertussis. Participants with higher SELFY-MPI scores were more likely to report vaccination against pneumococcus (45.6 vs. 28.3%, <i>p</i> = 0.01), whilst no significant differences were observed for the other vaccinations. In conclusion, the coverage of recommended vaccinations is low. Higher SELFY-MPI scores and vaccination status, particularly anti-pneumococcus, appear to be associated, but future studies are urgently needed for confirming that frailty is associated with vaccination status in older people.https://www.mdpi.com/2076-393X/10/4/555multidimensional prognostic indexvaccinationinfluenzaherpes zosterpneumococcusdiphtheria-tetanus-pertussis |
| spellingShingle | Nicola Veronese Giusy Vassallo Maria Armata Laura Cilona Salvatore Casalicchio Roberta Masnata Claudio Costantino Francesco Vitale Giovanni Maurizio Giammanco Stefania Maggi Shaun Sabico Nasser M. Al-Daghri Ligia J. Dominguez Mario Barbagallo Multidimensional Frailty and Vaccinations in Older People: A Cross-Sectional Study Vaccines multidimensional prognostic index vaccination influenza herpes zoster pneumococcus diphtheria-tetanus-pertussis |
| title | Multidimensional Frailty and Vaccinations in Older People: A Cross-Sectional Study |
| title_full | Multidimensional Frailty and Vaccinations in Older People: A Cross-Sectional Study |
| title_fullStr | Multidimensional Frailty and Vaccinations in Older People: A Cross-Sectional Study |
| title_full_unstemmed | Multidimensional Frailty and Vaccinations in Older People: A Cross-Sectional Study |
| title_short | Multidimensional Frailty and Vaccinations in Older People: A Cross-Sectional Study |
| title_sort | multidimensional frailty and vaccinations in older people a cross sectional study |
| topic | multidimensional prognostic index vaccination influenza herpes zoster pneumococcus diphtheria-tetanus-pertussis |
| url | https://www.mdpi.com/2076-393X/10/4/555 |
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