Topical 0.03% atropine vs. 15% aluminum chloride in treating multiple eccrine hidrocystomas: A randomized single blind controlled study
<b>Background:</b> Multiple eccrine hidrocystomas pose a significant treatment challenge due to their facial location and tendency to scar after traditional surgical and other destructive modalities. <b> Aims:</b> To compare two frequently used non-destructive therapeutic m...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2010-01-01
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| Series: | Indian Journal of Dermatology |
| Subjects: | |
| Online Access: | http://www.e-ijd.org/article.asp?issn=0019-5154;year=2010;volume=55;issue=1;spage=47;epage=49;aulast=Amirhoushang |
| Summary: | <b>Background:</b> Multiple eccrine hidrocystomas pose a significant treatment challenge due to their facial location and tendency to scar after traditional surgical and other destructive modalities. <b> Aims:</b> To compare two frequently used non-destructive therapeutic modalities. <b> Materials and Methods:</b> Thirty patients with multiple eccrine hidrocystomas were enrolled in the study. They used topical 0.03% Atropine cream and 15% AlCl<sub> 3</sub> solution on left and right sides of their face randomly for 4 weeks. All the patients were visited before commencing the therapy as well as two and four weeks later by a dermatologist, blinded to the drugs and the number of lesions. <b> Results:</b> Twenty nine patients (25 females, four males) completed the study. The mean reduction in the number of lesions was significantly higher with Atropine cream in comparison with AlCl<sub> 3</sub> solution, 10.2±7.4 vs. 6.2±5.3 (<i> P</i> < 0.05). There were no recurrences after three months follow-up in both groups. <b> Conclusion:</b> It seems that both Atropine and AlCl<sub> 3</sub> are useful therapies in eccrine hidrocytomas but the former might be more effective. We think that other randomized clinical trials with larger sample sizes are needed. |
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| ISSN: | 0019-5154 1998-3611 |