Topical 0.03% atropine vs. 15% aluminum chloride in treating multiple eccrine hidrocystomas: A randomized single blind controlled study
<b>Background:</b> Multiple eccrine hidrocystomas pose a significant treatment challenge due to their facial location and tendency to scar after traditional surgical and other destructive modalities. <b> Aims:</b> To compare two frequently used non-destructive therapeutic m...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2010-01-01
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| Series: | Indian Journal of Dermatology |
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| Online Access: | http://www.e-ijd.org/article.asp?issn=0019-5154;year=2010;volume=55;issue=1;spage=47;epage=49;aulast=Amirhoushang |
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| author | Amirhoushang Ehsani Mostafa Mirshams Maryam Akhyani Pardis Noormohamadpour Pedram Noormohamadpour |
| author_facet | Amirhoushang Ehsani Mostafa Mirshams Maryam Akhyani Pardis Noormohamadpour Pedram Noormohamadpour |
| author_sort | Amirhoushang Ehsani |
| collection | DOAJ |
| description | <b>Background:</b> Multiple eccrine hidrocystomas pose a significant treatment challenge due to their facial location and tendency to scar after traditional surgical and other destructive modalities. <b> Aims:</b> To compare two frequently used non-destructive therapeutic modalities. <b> Materials and Methods:</b> Thirty patients with multiple eccrine hidrocystomas were enrolled in the study. They used topical 0.03% Atropine cream and 15% AlCl<sub> 3</sub> solution on left and right sides of their face randomly for 4 weeks. All the patients were visited before commencing the therapy as well as two and four weeks later by a dermatologist, blinded to the drugs and the number of lesions. <b> Results:</b> Twenty nine patients (25 females, four males) completed the study. The mean reduction in the number of lesions was significantly higher with Atropine cream in comparison with AlCl<sub> 3</sub> solution, 10.2±7.4 vs. 6.2±5.3 (<i> P</i> < 0.05). There were no recurrences after three months follow-up in both groups. <b> Conclusion:</b> It seems that both Atropine and AlCl<sub> 3</sub> are useful therapies in eccrine hidrocytomas but the former might be more effective. We think that other randomized clinical trials with larger sample sizes are needed. |
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| format | Article |
| id | doaj.art-518ac2ff5c504e86b4ef2d1ead45312b |
| institution | Directory Open Access Journal |
| issn | 0019-5154 1998-3611 |
| language | English |
| last_indexed | 2024-12-13T14:08:58Z |
| publishDate | 2010-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Dermatology |
| spelling | doaj.art-518ac2ff5c504e86b4ef2d1ead45312b2022-12-21T23:42:31ZengWolters Kluwer Medknow PublicationsIndian Journal of Dermatology0019-51541998-36112010-01-015514749Topical 0.03% atropine vs. 15% aluminum chloride in treating multiple eccrine hidrocystomas: A randomized single blind controlled studyAmirhoushang EhsaniMostafa MirshamsMaryam AkhyaniPardis NoormohamadpourPedram Noormohamadpour<b>Background:</b> Multiple eccrine hidrocystomas pose a significant treatment challenge due to their facial location and tendency to scar after traditional surgical and other destructive modalities. <b> Aims:</b> To compare two frequently used non-destructive therapeutic modalities. <b> Materials and Methods:</b> Thirty patients with multiple eccrine hidrocystomas were enrolled in the study. They used topical 0.03% Atropine cream and 15% AlCl<sub> 3</sub> solution on left and right sides of their face randomly for 4 weeks. All the patients were visited before commencing the therapy as well as two and four weeks later by a dermatologist, blinded to the drugs and the number of lesions. <b> Results:</b> Twenty nine patients (25 females, four males) completed the study. The mean reduction in the number of lesions was significantly higher with Atropine cream in comparison with AlCl<sub> 3</sub> solution, 10.2±7.4 vs. 6.2±5.3 (<i> P</i> < 0.05). There were no recurrences after three months follow-up in both groups. <b> Conclusion:</b> It seems that both Atropine and AlCl<sub> 3</sub> are useful therapies in eccrine hidrocytomas but the former might be more effective. We think that other randomized clinical trials with larger sample sizes are needed.http://www.e-ijd.org/article.asp?issn=0019-5154;year=2010;volume=55;issue=1;spage=47;epage=49;aulast=AmirhoushangAtropinealuminum chloridemultiple eccrine hidrocystomas |
| spellingShingle | Amirhoushang Ehsani Mostafa Mirshams Maryam Akhyani Pardis Noormohamadpour Pedram Noormohamadpour Topical 0.03% atropine vs. 15% aluminum chloride in treating multiple eccrine hidrocystomas: A randomized single blind controlled study Indian Journal of Dermatology Atropine aluminum chloride multiple eccrine hidrocystomas |
| title | Topical 0.03% atropine vs. 15% aluminum chloride in treating multiple eccrine hidrocystomas: A randomized single blind controlled study |
| title_full | Topical 0.03% atropine vs. 15% aluminum chloride in treating multiple eccrine hidrocystomas: A randomized single blind controlled study |
| title_fullStr | Topical 0.03% atropine vs. 15% aluminum chloride in treating multiple eccrine hidrocystomas: A randomized single blind controlled study |
| title_full_unstemmed | Topical 0.03% atropine vs. 15% aluminum chloride in treating multiple eccrine hidrocystomas: A randomized single blind controlled study |
| title_short | Topical 0.03% atropine vs. 15% aluminum chloride in treating multiple eccrine hidrocystomas: A randomized single blind controlled study |
| title_sort | topical 0 03 x0025 atropine vs 15 x0025 aluminum chloride in treating multiple eccrine hidrocystomas a randomized single blind controlled study |
| topic | Atropine aluminum chloride multiple eccrine hidrocystomas |
| url | http://www.e-ijd.org/article.asp?issn=0019-5154;year=2010;volume=55;issue=1;spage=47;epage=49;aulast=Amirhoushang |
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