Identification of Epigallocatechin-3-Gallate (EGCG) from Green Tea Using Mass Spectrometry
In an era where humanity is reinstating its lost hope and expectation on natural products, green tea occupies quite a position for what it has proven to be, in its endeavors for human welfare and health. Epigallocatechin-3-gallate (EGCG) is the key to the vast biological activities of green tea. Gre...
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MDPI AG
2022-08-01
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| Online Access: | https://www.mdpi.com/2297-8739/9/8/209 |
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| author | Iyyakkannu Sivanesan Manikandan Muthu Anusha Kannan Suraj Shiv Charan Pushparaj Jae-Wook Oh Judy Gopal |
| author_facet | Iyyakkannu Sivanesan Manikandan Muthu Anusha Kannan Suraj Shiv Charan Pushparaj Jae-Wook Oh Judy Gopal |
| author_sort | Iyyakkannu Sivanesan |
| collection | DOAJ |
| description | In an era where humanity is reinstating its lost hope and expectation on natural products, green tea occupies quite a position for what it has proven to be, in its endeavors for human welfare and health. Epigallocatechin-3-gallate (EGCG) is the key to the vast biological activities of green tea. Green tea is no longer in the backdrop; it has emerged as the most viral, trending bioactive molecule when it comes to health benefits for human beings. This review focuses on the use of various analytical techniques for the analysis of EGCG. That which has been achieved so far, in terms of in vitro, pure component analysis, as well as those spikes in biological fluids and those in vivo in animal and human samples, was surveyed and presented. The use of MS-based techniques for the analysis of EGCG is elaborately reviewed and the need for improvising the applications is explained. The review emphasizes that there is plenty of room to explore matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) applications in this subject area. |
| first_indexed | 2024-03-09T03:50:24Z |
| format | Article |
| id | doaj.art-518cc97e2f3c4f8192092c6fedc0f397 |
| institution | Directory Open Access Journal |
| issn | 2297-8739 |
| language | English |
| last_indexed | 2024-03-09T03:50:24Z |
| publishDate | 2022-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Separations |
| spelling | doaj.art-518cc97e2f3c4f8192092c6fedc0f3972023-12-03T14:28:07ZengMDPI AGSeparations2297-87392022-08-019820910.3390/separations9080209Identification of Epigallocatechin-3-Gallate (EGCG) from Green Tea Using Mass SpectrometryIyyakkannu Sivanesan0Manikandan Muthu1Anusha Kannan2Suraj Shiv Charan Pushparaj3Jae-Wook Oh4Judy Gopal5Department of Bioresources and Food Science, Institute of Natural Science and Agriculture, Konkuk University, 1 Hwayang-dong, Gwangjin-gu, Seoul 05029, KoreaDepartment of Research and Innovation, Saveetha School of Engineering, Saveetha Institute of Medical and Technical Sciences (SIMATS), Chennai 602 105, Tamil Nadu, IndiaSchool of Computer Science and Engineering, Vellore Institute of Technology, Chennai 600 127, Tamil Nadu, IndiaDepartment of Research and Innovation, Saveetha School of Engineering, Saveetha Institute of Medical and Technical Sciences (SIMATS), Chennai 602 105, Tamil Nadu, IndiaDepartment of Stem Cell and Regenerative Biotechnology, Konkuk University, Seoul 05029, KoreaDepartment of Research and Innovation, Saveetha School of Engineering, Saveetha Institute of Medical and Technical Sciences (SIMATS), Chennai 602 105, Tamil Nadu, IndiaIn an era where humanity is reinstating its lost hope and expectation on natural products, green tea occupies quite a position for what it has proven to be, in its endeavors for human welfare and health. Epigallocatechin-3-gallate (EGCG) is the key to the vast biological activities of green tea. Green tea is no longer in the backdrop; it has emerged as the most viral, trending bioactive molecule when it comes to health benefits for human beings. This review focuses on the use of various analytical techniques for the analysis of EGCG. That which has been achieved so far, in terms of in vitro, pure component analysis, as well as those spikes in biological fluids and those in vivo in animal and human samples, was surveyed and presented. The use of MS-based techniques for the analysis of EGCG is elaborately reviewed and the need for improvising the applications is explained. The review emphasizes that there is plenty of room to explore matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) applications in this subject area.https://www.mdpi.com/2297-8739/9/8/209catechinsEGCGmass spectrometrydetectiongreen teaLC-MS |
| spellingShingle | Iyyakkannu Sivanesan Manikandan Muthu Anusha Kannan Suraj Shiv Charan Pushparaj Jae-Wook Oh Judy Gopal Identification of Epigallocatechin-3-Gallate (EGCG) from Green Tea Using Mass Spectrometry Separations catechins EGCG mass spectrometry detection green tea LC-MS |
| title | Identification of Epigallocatechin-3-Gallate (EGCG) from Green Tea Using Mass Spectrometry |
| title_full | Identification of Epigallocatechin-3-Gallate (EGCG) from Green Tea Using Mass Spectrometry |
| title_fullStr | Identification of Epigallocatechin-3-Gallate (EGCG) from Green Tea Using Mass Spectrometry |
| title_full_unstemmed | Identification of Epigallocatechin-3-Gallate (EGCG) from Green Tea Using Mass Spectrometry |
| title_short | Identification of Epigallocatechin-3-Gallate (EGCG) from Green Tea Using Mass Spectrometry |
| title_sort | identification of epigallocatechin 3 gallate egcg from green tea using mass spectrometry |
| topic | catechins EGCG mass spectrometry detection green tea LC-MS |
| url | https://www.mdpi.com/2297-8739/9/8/209 |
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