AMPKα2 regulates fasting-induced hyperketonemia by suppressing SCOT ubiquitination and degradation

Abstract Ketone bodies serve as an energy source, especially in the absence of carbohydrates or in the extended exercise. Adenosine monophosphate (AMP)-activated protein kinase (AMPK) is a crucial energy sensor that regulates lipid and glucose metabolism. However, whether AMPK regulates ketone metab...

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Bibliographic Details
Main Authors: Lingxue Zhang, Yanqiao Lu, Junqing An, Yin Wu, Zhixue Liu, Ming-Hui Zou
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-49991-5