Effect of L-carnitine on quality of life in covert hepatic encephalopathy: a randomized, double-blind, placebo-controlled study

Effect of L-carnitine on quality of life in covert hepatic encephalopathy: a randomized, double-blind, placebo-controlled study

Background/Aims L-carnitine is potentially beneficial in patients with hepatic encephalopathy (HE). We aimed to evaluate the impact of L-carnitine on the quality of life and liver function in patients with liver cirrhosis and covert HE. Methods We conducted an investigator-initiated, prospective, mu...

Full description

Bibliographic Details
Main Authors:	Eileen L. Yoon, Sang Bong Ahn, Dae Won Jun, Yong Kyun Cho, Do Seon Song, Jae Yoon Jeong, Hee Yeon Kim, Young Kul Jung, Myeong Jun Song, Sung Eun Kim, Hyoung Su Kim, Soung Won Jeong, Sang Gyune Kim, Tae Hee Lee
Format:	Article
Language:	English
Published:	The Korean Association of Internal Medicine 2022-07-01
Series:	The Korean Journal of Internal Medicine
Subjects:	carnitine liver cirrhosis hepatic encephalopathy randomized controlled trials as topic stroop test
Online Access:	http://kjim.org/upload/pdf/kjim-2021-338.pdf

Similar Items

Systemic primary carnitine deficiency with hypoglycemic encephalopathy
by: Jae Sung Jun, et al.
Published: (2016-12-01)

USE OF THE STROOP ENCEPHALAPP FOR COVERT HEPATIC ENCEPHALOPATHY SCREENING IN CIRRHOTIC PATIENTS IN SOUTHERN BRAZIL
by: Paulo André Bispo MACHADO JÚNIOR, et al.
Published: (2020-11-01)

Performance of EncephalApp Stroop Test in Cirrhotic Patients for Evaluating Covert Hepatic Encephalopathy
by: Juferdy Kurniawan, et al.
Published: (2023-07-01)

Usefulness of Carnitine Supplementation for the Complications of Liver Cirrhosis
by: Tatsunori Hanai, et al.
Published: (2020-06-01)

EncephalApp Stroop Test as a Screening Tool for the Detection of Minimal Hepatic Encephalopathy in Patients with Cirrhosis—Single-Center Experience
by: Marko Vojnovic, et al.
Published: (2024-03-01)

EncephalApp Stroop Test validation for the screening of minimal hepatic encephalopathy in Brazil
by: Marlone Cunha-Silva, et al.
Published: (2022-01-01)

Valproate induced hyperammonemic encephalopathy: a rare adverse effect of a common drug
by: Sanaullah Mudassir, et al.
Published: (2023-12-01)

Carnitine Inborn Errors of Metabolism
by: Mohammed Almannai, et al.
Published: (2019-09-01)

Efficacy and safety of entecavir plus carnitine complex (GODEX®) compared to entecavir monotherapy in patient with ALT elevated chronic hepatitis B: randomized, multicenter open-label trials. The GOAL study
by: Dae Won Jun, et al.
Published: (2013-06-01)

The Mitochondrial Carnitine Acyl-carnitine Carrier (SLC25A20): Molecular Mechanisms of Transport, Role in Redox Sensing and Interaction with Drugs
by: Annamaria Tonazzi, et al.
Published: (2021-03-01)

Impact of <span style="font-variant: small-caps">l</span>-Carnitine Supplementation on Liver Enzyme Normalization in Patients with Chronic Liver Disease: A Meta-Analysis of Randomized Trials
by: Hyunwoo Oh, et al.
Published: (2022-06-01)

The Effects of L-Carnitine, Acetyl-L-Carnitine, and Propionyl-L-Carnitine on Body Mass in Type 2 Diabetes Mellitus Patients
by: Dong-Dong Wang, et al.
Published: (2021-11-01)

Neuroprotective effects of L-carnitine against oxygen-glucose deprivation in rat primary cortical neurons
by: Yu Jin Kim, et al.
Published: (2012-07-01)

Carnitine in Alleviation of Complications Caused by Acute Valproic Acid Toxicity; an Exprimental Study on Mice
by: Akram Jamshidzadeh, et al.
Published: (2023-12-01)

A Combination of Soy Isoflavone and L-Carnitine Improves Running Endurance in Mice
by: Jaewon Lee, et al.
Published: (2023-08-01)

Proximate Composition, and -Carnitine and Betaine Contents in Meat from Korean Indigenous Chicken
by: Samooel Jung, et al.
Published: (2015-12-01)

Carnitine Orotate Complex Ameliorates Insulin Resistance and Hepatic Steatosis Through Carnitine Acetyltransferase Pathway
by: Jung-Hee Hong, et al.
Published: (2021-11-01)

Impact of protein and carnitine consuption on outcomes of care development of full-term newborns with critical perinatal diseases
by: I.O. Anikin, et al.
Published: (2024-04-01)

Acyl-Carnitines Exert Positive Effects on Mitochondrial Activity under Oxidative Stress in Mouse Oocytes: A Potential Mechanism Underlying Carnitine Efficacy on PCOS
by: Martina Placidi, et al.
Published: (2023-09-01)

Critical update for the clinical use of L-carnitine analogs in cardiometabolic disorders
by: Herrera MD, et al.
Published: (2011-03-01)

Neonatal Hypoxic-Ischemic Brain Injury Alters Brain Acylcarnitine Levels in a Mouse Model
by: Amanda M. Dave, et al.
Published: (2022-05-01)

Alterations in gut virome are associated with cognitive function and minimal hepatic encephalopathy cross-sectionally and longitudinally in cirrhosis
by: Thananya Jinato, et al.
Published: (2023-12-01)

Impact of haemodialysis on plasma carnitine concentrations in haemodialysis patients
by: Sadia Rehman, et al.
Published: (2023-11-01)

Serum S100B Levels in Patients with Liver Cirrhosis and Hepatic Encephalopathy
by: Mo-Jong Kim, et al.
Published: (2023-01-01)

L-carnitine supplementation in female infertility – is it working?
by: Paulina Laskus, et al.
Published: (2023-05-01)

The effect of melatonin and carnitine on radiation nephropathy
by: Ozge Ozdemir, et al.
Published: (2022-01-01)

Carnitine and Depression
by: Ting Liu, et al.
Published: (2022-03-01)

Newborn Screening for Mitochondrial Carnitine-Acylcarnitine Cycle Disorders in Zhejiang Province, China
by: Duo Zhou, et al.
Published: (2022-03-01)

Reversible splenial lesion on the corpus callosum in nonfulminant hepatitis A presenting as encephalopathy
by: Soon Young Ko, et al.
Published: (2014-12-01)

Preventive Role of L-Carnitine and Balanced Diet in Alzheimer’s Disease
by: Alina Kepka, et al.
Published: (2020-07-01)

Effects of oral L-carnitine and DL-carnitine supplementation on alloxan-diabetic rats
by: Roberto Barbosa Bazotte, et al.
Published: (2012-02-01)

Regulatory Functions of L-Carnitine, Acetyl, and Propionyl L-Carnitine in a PCOS Mouse Model: Focus on Antioxidant/Antiglycative Molecular Pathways in the Ovarian Microenvironment
by: Giovanna Di Emidio, et al.
Published: (2020-09-01)

Caffeine ingestion stimulates plasma carnitine clearance in humans
by: Benjamin T. Wall, et al.
Published: (2023-02-01)

Assessment of Seminal L-Carnitine in Infertile Men with Varicocele
by: Mohamed Aabdallah, et al.
Published: (2022-04-01)

Assessment of carnitine excretion and its ratio to plasma free carnitine as a biomarker for primary carnitine deficiency in newborns
by: Loek L. Crefcoeur, et al.
Published: (2023-01-01)

Pheochromocytoma Presenting with Hypertensive Encephalopathy in a 12-Year-Old Boy
by: Jung Heon Kim, et al.
Published: (2015-06-01)

Phenylephrine Induced Posterior Reversible Encephalopathy Syndrome during Resection of Solitary Pulmonary Nodule
by: Soon Ho Hong, et al.
Published: (2017-06-01)

Effect and mechanism of L-carnitine on corneal epithelial repair after alkali burn
by: Bing-Jie Yu, et al.
Published: (2021-07-01)

Simultaneous determination of L-carnitine and D-carnitine in infant formula by pre-column derivation high performance liquid chromatography
by: LI Shucai, et al.
Published: (2022-07-01)

L-carnitine supplementation in the recovery of plasma L-carnitine in patients with heart failure submitted to coronary artery bypass grafting
by: WANISE M. SOUZA CRUZ, et al.