Impact of the COVID-19 Pandemic on the Management of <i>Staphylococcus aureus</i> Bloodstream Infections in a Tertiary Care Hospital
<i>Staphylococcus aureus</i> bacteremia (SAB) is associated with a high mortality rate. The clinical outcome of SAB patients highly depends on early diagnosis, adequate antibiotic therapy and source control. In the context of the COVID-19 pandemic, the health care system faced additional...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-04-01
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| Series: | Pathogens |
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| Online Access: | https://www.mdpi.com/2076-0817/12/4/611 |
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| author | Christian W. Böing Neele J. Froböse Frieder Schaumburg Stefanie Kampmeier |
| author_facet | Christian W. Böing Neele J. Froböse Frieder Schaumburg Stefanie Kampmeier |
| author_sort | Christian W. Böing |
| collection | DOAJ |
| description | <i>Staphylococcus aureus</i> bacteremia (SAB) is associated with a high mortality rate. The clinical outcome of SAB patients highly depends on early diagnosis, adequate antibiotic therapy and source control. In the context of the COVID-19 pandemic, the health care system faced additional organizational challenges and the question arose whether structured screening and triaging for COVID-19 and shifting resources influence the management of SAB. Patients (<i>n</i> = 115) with SAB were enrolled in a retrospective comparative study with historical controls (March 2019–February 2021). The quality of SAB therapy was assessed with a point score, which included correct choice of antibiotic, adequate dosage of antibiotic, sufficient duration of therapy, early start of therapy after receipt of findings, focus search and taking control blood cultures 3–4 days after starting adequate antibiotic therapy. The quality of treatment before and after the onset of the COVID-19 pandemic were compared. No significant differences in the total score points were found between the pre-COVID-19 and COVID-19 cohort. All quality indicators, except the correct duration of antibiotic therapy, showed no significant differences in both cohorts. Furthermore, there were no significant differences in the outcome between both cohorts. The treatment quality of SAB therapy was comparable before and during the COVID-19 pandemic. |
| first_indexed | 2024-03-11T04:39:14Z |
| format | Article |
| id | doaj.art-519dba1400e641768a6cebbf29c9fbba |
| institution | Directory Open Access Journal |
| issn | 2076-0817 |
| language | English |
| last_indexed | 2024-03-11T04:39:14Z |
| publishDate | 2023-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Pathogens |
| spelling | doaj.art-519dba1400e641768a6cebbf29c9fbba2023-11-17T20:49:11ZengMDPI AGPathogens2076-08172023-04-0112461110.3390/pathogens12040611Impact of the COVID-19 Pandemic on the Management of <i>Staphylococcus aureus</i> Bloodstream Infections in a Tertiary Care HospitalChristian W. Böing0Neele J. Froböse1Frieder Schaumburg2Stefanie Kampmeier3Institute of Hygiene, University Hospital Münster, Robert-Koch-Straße 41, 48149 Münster, GermanyInstitute of Medical Microbiology, Domagkstraße 10, 48149 Münster, GermanyInstitute of Medical Microbiology, Domagkstraße 10, 48149 Münster, GermanyInstitute of Hygiene, University Hospital Münster, Robert-Koch-Straße 41, 48149 Münster, Germany<i>Staphylococcus aureus</i> bacteremia (SAB) is associated with a high mortality rate. The clinical outcome of SAB patients highly depends on early diagnosis, adequate antibiotic therapy and source control. In the context of the COVID-19 pandemic, the health care system faced additional organizational challenges and the question arose whether structured screening and triaging for COVID-19 and shifting resources influence the management of SAB. Patients (<i>n</i> = 115) with SAB were enrolled in a retrospective comparative study with historical controls (March 2019–February 2021). The quality of SAB therapy was assessed with a point score, which included correct choice of antibiotic, adequate dosage of antibiotic, sufficient duration of therapy, early start of therapy after receipt of findings, focus search and taking control blood cultures 3–4 days after starting adequate antibiotic therapy. The quality of treatment before and after the onset of the COVID-19 pandemic were compared. No significant differences in the total score points were found between the pre-COVID-19 and COVID-19 cohort. All quality indicators, except the correct duration of antibiotic therapy, showed no significant differences in both cohorts. Furthermore, there were no significant differences in the outcome between both cohorts. The treatment quality of SAB therapy was comparable before and during the COVID-19 pandemic.https://www.mdpi.com/2076-0817/12/4/611<i>Staphylococcus aureus</i>bacteremiaCOVID-19antimicrobial stewardship |
| spellingShingle | Christian W. Böing Neele J. Froböse Frieder Schaumburg Stefanie Kampmeier Impact of the COVID-19 Pandemic on the Management of <i>Staphylococcus aureus</i> Bloodstream Infections in a Tertiary Care Hospital Pathogens <i>Staphylococcus aureus</i> bacteremia COVID-19 antimicrobial stewardship |
| title | Impact of the COVID-19 Pandemic on the Management of <i>Staphylococcus aureus</i> Bloodstream Infections in a Tertiary Care Hospital |
| title_full | Impact of the COVID-19 Pandemic on the Management of <i>Staphylococcus aureus</i> Bloodstream Infections in a Tertiary Care Hospital |
| title_fullStr | Impact of the COVID-19 Pandemic on the Management of <i>Staphylococcus aureus</i> Bloodstream Infections in a Tertiary Care Hospital |
| title_full_unstemmed | Impact of the COVID-19 Pandemic on the Management of <i>Staphylococcus aureus</i> Bloodstream Infections in a Tertiary Care Hospital |
| title_short | Impact of the COVID-19 Pandemic on the Management of <i>Staphylococcus aureus</i> Bloodstream Infections in a Tertiary Care Hospital |
| title_sort | impact of the covid 19 pandemic on the management of i staphylococcus aureus i bloodstream infections in a tertiary care hospital |
| topic | <i>Staphylococcus aureus</i> bacteremia COVID-19 antimicrobial stewardship |
| url | https://www.mdpi.com/2076-0817/12/4/611 |
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