High-level levofloxacin-resistant emm12 group A Streptococcus, 2012–2018: A multicenter study in Taiwan
High-level levofloxacin-resistant group A Streptococcus emerged in Taiwan in 2012. Among the 24 isolates identified, 23 belonged to emm12/ST36, most harbored the same GyrA and ParC mutations and were highly clonal. wgMLST showed them to be closely related to the Hong Kong scarlet fever outbreak stra...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-08-01
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| Series: | Journal of Microbiology, Immunology and Infection |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1684118223000889 |
| _version_ | 1797749166546354176 |
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| author | Ying-Chi Huang Jui-Fen Lai Chi-Jung Wu I-Wen Huang Shu-Chen Kuo Ching-Len Liao Tzu-Wen Huang Tsai-Ling Lauderdale |
| author_facet | Ying-Chi Huang Jui-Fen Lai Chi-Jung Wu I-Wen Huang Shu-Chen Kuo Ching-Len Liao Tzu-Wen Huang Tsai-Ling Lauderdale |
| author_sort | Ying-Chi Huang |
| collection | DOAJ |
| description | High-level levofloxacin-resistant group A Streptococcus emerged in Taiwan in 2012. Among the 24 isolates identified, 23 belonged to emm12/ST36, most harbored the same GyrA and ParC mutations and were highly clonal. wgMLST showed them to be closely related to the Hong Kong scarlet fever outbreak strains. Continuous surveillance is warranted. |
| first_indexed | 2024-03-12T16:15:26Z |
| format | Article |
| id | doaj.art-51a0be10a257431296d7987ac2129121 |
| institution | Directory Open Access Journal |
| issn | 1684-1182 |
| language | English |
| last_indexed | 2024-03-12T16:15:26Z |
| publishDate | 2023-08-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Microbiology, Immunology and Infection |
| spelling | doaj.art-51a0be10a257431296d7987ac21291212023-08-09T04:32:18ZengElsevierJournal of Microbiology, Immunology and Infection1684-11822023-08-01564875879High-level levofloxacin-resistant emm12 group A Streptococcus, 2012–2018: A multicenter study in TaiwanYing-Chi Huang0Jui-Fen Lai1Chi-Jung Wu2I-Wen Huang3Shu-Chen Kuo4Ching-Len Liao5Tzu-Wen Huang6Tsai-Ling Lauderdale7National Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Zhunan, TaiwanNational Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Zhunan, TaiwanNational Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Zhunan, Taiwan; Department of Internal Medicine, National Cheng Kung University Hospital, National Cheng Kung University, Tainan, TaiwanNational Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Zhunan, TaiwanNational Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Zhunan, TaiwanNational Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Zhunan, TaiwanDepartment of Microbiology and Immunology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan; Corresponding author. Department of Microbiology and Immunology, School of Medicine, College of Medicine, Taipei Medical University; Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei 11031, Taiwan.National Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Zhunan, Taiwan; Corresponding author. National Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, No.35, Keyan Road, Zhunan, Miaoli County 35053, Taiwan.High-level levofloxacin-resistant group A Streptococcus emerged in Taiwan in 2012. Among the 24 isolates identified, 23 belonged to emm12/ST36, most harbored the same GyrA and ParC mutations and were highly clonal. wgMLST showed them to be closely related to the Hong Kong scarlet fever outbreak strains. Continuous surveillance is warranted.http://www.sciencedirect.com/science/article/pii/S1684118223000889Group A StreptococcusStreptococcus pyogenesemm typeLevofloxacin-nonsusceptibleemm12 |
| spellingShingle | Ying-Chi Huang Jui-Fen Lai Chi-Jung Wu I-Wen Huang Shu-Chen Kuo Ching-Len Liao Tzu-Wen Huang Tsai-Ling Lauderdale High-level levofloxacin-resistant emm12 group A Streptococcus, 2012–2018: A multicenter study in Taiwan Journal of Microbiology, Immunology and Infection Group A Streptococcus Streptococcus pyogenes emm type Levofloxacin-nonsusceptible emm12 |
| title | High-level levofloxacin-resistant emm12 group A Streptococcus, 2012–2018: A multicenter study in Taiwan |
| title_full | High-level levofloxacin-resistant emm12 group A Streptococcus, 2012–2018: A multicenter study in Taiwan |
| title_fullStr | High-level levofloxacin-resistant emm12 group A Streptococcus, 2012–2018: A multicenter study in Taiwan |
| title_full_unstemmed | High-level levofloxacin-resistant emm12 group A Streptococcus, 2012–2018: A multicenter study in Taiwan |
| title_short | High-level levofloxacin-resistant emm12 group A Streptococcus, 2012–2018: A multicenter study in Taiwan |
| title_sort | high level levofloxacin resistant emm12 group a streptococcus 2012 2018 a multicenter study in taiwan |
| topic | Group A Streptococcus Streptococcus pyogenes emm type Levofloxacin-nonsusceptible emm12 |
| url | http://www.sciencedirect.com/science/article/pii/S1684118223000889 |
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