A Comparison of Verapamil and Digoxin for Heart Rate Control in Atrial Fibrillation
Purpose: Atrial fibrillation (AF) is one of the most common types of sustained dysrhythmia and there are some disagreements about its treatment. The goals of AF treatment include the control of ventricular rate, the establishment of sinus rhythm and the prevention of thromboembolic events. In this s...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Tabriz University of Medical Sciences
2012-08-01
|
| Series: | Advanced Pharmaceutical Bulletin |
| Subjects: | |
| Online Access: | http://journals.tbzmed.ac.ir/PDF/APB/Manuscript/APB-2-201.pdf |
| _version_ | 1811258045198499840 |
|---|---|
| author | Mohammad Afzali Moghadam Maryam Fadaie Dashti Kavous Shahsavarinia Ata Mahmoodpoor Kazem Jamali |
| author_facet | Mohammad Afzali Moghadam Maryam Fadaie Dashti Kavous Shahsavarinia Ata Mahmoodpoor Kazem Jamali |
| author_sort | Mohammad Afzali Moghadam |
| collection | DOAJ |
| description | Purpose: Atrial fibrillation (AF) is one of the most common types of sustained dysrhythmia and there are some disagreements about its treatment. The goals of AF treatment include the control of ventricular rate, the establishment of sinus rhythm and the prevention of thromboembolic events. In this study, the effect of verapamil was compared to digoxin on heart rate control in patients with AF. Methods:This descriptive study was conducted in an emergency department (ED) in Iran. Sixty patients with a new onset AF and rapid ventricular response receiving digoxin or verapamil were included and observed. Results:Two thirty-patient groups receiving verapamil or digoxin were evaluated. The heart rate was significantly decreased in both groups (p = 0.002); however, the cardioversion was not noticed in both of them. The best rate control in verapamil and digoxin groups was observed after 5.9 mg (46.7%) and 0.6 mg (36.7%), respectively. Conclusion: Administration of verapamil in comparison with digoxin has no difference to control the heart rate in AF patients. It should be taken into consideration that prospective randomized studies should be conducted to identify the efficacy and select the best of these two drugs to treat AF patients. |
| first_indexed | 2024-04-12T18:07:14Z |
| format | Article |
| id | doaj.art-51a0f5bf55254d5b9e6d2fa2871c278b |
| institution | Directory Open Access Journal |
| issn | 2228-5881 2251-7308 |
| language | English |
| last_indexed | 2024-04-12T18:07:14Z |
| publishDate | 2012-08-01 |
| publisher | Tabriz University of Medical Sciences |
| record_format | Article |
| series | Advanced Pharmaceutical Bulletin |
| spelling | doaj.art-51a0f5bf55254d5b9e6d2fa2871c278b2022-12-22T03:21:57ZengTabriz University of Medical SciencesAdvanced Pharmaceutical Bulletin2228-58812251-73082012-08-0122201205A Comparison of Verapamil and Digoxin for Heart Rate Control in Atrial FibrillationMohammad Afzali MoghadamMaryam Fadaie DashtiKavous ShahsavariniaAta MahmoodpoorKazem JamaliPurpose: Atrial fibrillation (AF) is one of the most common types of sustained dysrhythmia and there are some disagreements about its treatment. The goals of AF treatment include the control of ventricular rate, the establishment of sinus rhythm and the prevention of thromboembolic events. In this study, the effect of verapamil was compared to digoxin on heart rate control in patients with AF. Methods:This descriptive study was conducted in an emergency department (ED) in Iran. Sixty patients with a new onset AF and rapid ventricular response receiving digoxin or verapamil were included and observed. Results:Two thirty-patient groups receiving verapamil or digoxin were evaluated. The heart rate was significantly decreased in both groups (p = 0.002); however, the cardioversion was not noticed in both of them. The best rate control in verapamil and digoxin groups was observed after 5.9 mg (46.7%) and 0.6 mg (36.7%), respectively. Conclusion: Administration of verapamil in comparison with digoxin has no difference to control the heart rate in AF patients. It should be taken into consideration that prospective randomized studies should be conducted to identify the efficacy and select the best of these two drugs to treat AF patients.http://journals.tbzmed.ac.ir/PDF/APB/Manuscript/APB-2-201.pdfDigoxinVerapamilTreatmentAtrial fibrillation |
| spellingShingle | Mohammad Afzali Moghadam Maryam Fadaie Dashti Kavous Shahsavarinia Ata Mahmoodpoor Kazem Jamali A Comparison of Verapamil and Digoxin for Heart Rate Control in Atrial Fibrillation Advanced Pharmaceutical Bulletin Digoxin Verapamil Treatment Atrial fibrillation |
| title | A Comparison of Verapamil and Digoxin for Heart Rate Control in Atrial Fibrillation |
| title_full | A Comparison of Verapamil and Digoxin for Heart Rate Control in Atrial Fibrillation |
| title_fullStr | A Comparison of Verapamil and Digoxin for Heart Rate Control in Atrial Fibrillation |
| title_full_unstemmed | A Comparison of Verapamil and Digoxin for Heart Rate Control in Atrial Fibrillation |
| title_short | A Comparison of Verapamil and Digoxin for Heart Rate Control in Atrial Fibrillation |
| title_sort | comparison of verapamil and digoxin for heart rate control in atrial fibrillation |
| topic | Digoxin Verapamil Treatment Atrial fibrillation |
| url | http://journals.tbzmed.ac.ir/PDF/APB/Manuscript/APB-2-201.pdf |
| work_keys_str_mv | AT mohammadafzalimoghadam acomparisonofverapamilanddigoxinforheartratecontrolinatrialfibrillation AT maryamfadaiedashti acomparisonofverapamilanddigoxinforheartratecontrolinatrialfibrillation AT kavousshahsavarinia acomparisonofverapamilanddigoxinforheartratecontrolinatrialfibrillation AT atamahmoodpoor acomparisonofverapamilanddigoxinforheartratecontrolinatrialfibrillation AT kazemjamali acomparisonofverapamilanddigoxinforheartratecontrolinatrialfibrillation AT mohammadafzalimoghadam comparisonofverapamilanddigoxinforheartratecontrolinatrialfibrillation AT maryamfadaiedashti comparisonofverapamilanddigoxinforheartratecontrolinatrialfibrillation AT kavousshahsavarinia comparisonofverapamilanddigoxinforheartratecontrolinatrialfibrillation AT atamahmoodpoor comparisonofverapamilanddigoxinforheartratecontrolinatrialfibrillation AT kazemjamali comparisonofverapamilanddigoxinforheartratecontrolinatrialfibrillation |