Antagonistic roles of Drosophila Tctp and Brahma in chromatin remodelling and stabilizing repeated sequences
Genome stability is important for normal cellular function. Here, Hong and Choi show that translationally controlled tumour protein (TCTP) in Drosophilaregulates pericentromeric chromatin remodelling and transcription via negatively regulating a chromatin remodeler Brahma.
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Format: | Article |
Language: | English |
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Nature Portfolio
2016-09-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/ncomms12988 |
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author | Sung-Tae Hong Kwang-Wook Choi |
author_facet | Sung-Tae Hong Kwang-Wook Choi |
author_sort | Sung-Tae Hong |
collection | DOAJ |
description | Genome stability is important for normal cellular function. Here, Hong and Choi show that translationally controlled tumour protein (TCTP) in Drosophilaregulates pericentromeric chromatin remodelling and transcription via negatively regulating a chromatin remodeler Brahma. |
first_indexed | 2024-12-13T16:18:50Z |
format | Article |
id | doaj.art-51a3a7112da34664b8f65bdd995733bb |
institution | Directory Open Access Journal |
issn | 2041-1723 |
language | English |
last_indexed | 2024-12-13T16:18:50Z |
publishDate | 2016-09-01 |
publisher | Nature Portfolio |
record_format | Article |
series | Nature Communications |
spelling | doaj.art-51a3a7112da34664b8f65bdd995733bb2022-12-21T23:38:46ZengNature PortfolioNature Communications2041-17232016-09-017111610.1038/ncomms12988Antagonistic roles of Drosophila Tctp and Brahma in chromatin remodelling and stabilizing repeated sequencesSung-Tae Hong0Kwang-Wook Choi1Department of Biological Sciences, Korea Advanced Institute of Science and TechnologyDepartment of Biological Sciences, Korea Advanced Institute of Science and TechnologyGenome stability is important for normal cellular function. Here, Hong and Choi show that translationally controlled tumour protein (TCTP) in Drosophilaregulates pericentromeric chromatin remodelling and transcription via negatively regulating a chromatin remodeler Brahma.https://doi.org/10.1038/ncomms12988 |
spellingShingle | Sung-Tae Hong Kwang-Wook Choi Antagonistic roles of Drosophila Tctp and Brahma in chromatin remodelling and stabilizing repeated sequences Nature Communications |
title | Antagonistic roles of Drosophila Tctp and Brahma in chromatin remodelling and stabilizing repeated sequences |
title_full | Antagonistic roles of Drosophila Tctp and Brahma in chromatin remodelling and stabilizing repeated sequences |
title_fullStr | Antagonistic roles of Drosophila Tctp and Brahma in chromatin remodelling and stabilizing repeated sequences |
title_full_unstemmed | Antagonistic roles of Drosophila Tctp and Brahma in chromatin remodelling and stabilizing repeated sequences |
title_short | Antagonistic roles of Drosophila Tctp and Brahma in chromatin remodelling and stabilizing repeated sequences |
title_sort | antagonistic roles of drosophila tctp and brahma in chromatin remodelling and stabilizing repeated sequences |
url | https://doi.org/10.1038/ncomms12988 |
work_keys_str_mv | AT sungtaehong antagonisticrolesofdrosophilatctpandbrahmainchromatinremodellingandstabilizingrepeatedsequences AT kwangwookchoi antagonisticrolesofdrosophilatctpandbrahmainchromatinremodellingandstabilizingrepeatedsequences |