Antagonistic roles of Drosophila Tctp and Brahma in chromatin remodelling and stabilizing repeated sequences

Genome stability is important for normal cellular function. Here, Hong and Choi show that translationally controlled tumour protein (TCTP) in Drosophilaregulates pericentromeric chromatin remodelling and transcription via negatively regulating a chromatin remodeler Brahma.

Bibliographic Details
Main Authors: Sung-Tae Hong, Kwang-Wook Choi
Format: Article
Language:English
Published: Nature Portfolio 2016-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms12988
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author Sung-Tae Hong
Kwang-Wook Choi
author_facet Sung-Tae Hong
Kwang-Wook Choi
author_sort Sung-Tae Hong
collection DOAJ
description Genome stability is important for normal cellular function. Here, Hong and Choi show that translationally controlled tumour protein (TCTP) in Drosophilaregulates pericentromeric chromatin remodelling and transcription via negatively regulating a chromatin remodeler Brahma.
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spelling doaj.art-51a3a7112da34664b8f65bdd995733bb2022-12-21T23:38:46ZengNature PortfolioNature Communications2041-17232016-09-017111610.1038/ncomms12988Antagonistic roles of Drosophila Tctp and Brahma in chromatin remodelling and stabilizing repeated sequencesSung-Tae Hong0Kwang-Wook Choi1Department of Biological Sciences, Korea Advanced Institute of Science and TechnologyDepartment of Biological Sciences, Korea Advanced Institute of Science and TechnologyGenome stability is important for normal cellular function. Here, Hong and Choi show that translationally controlled tumour protein (TCTP) in Drosophilaregulates pericentromeric chromatin remodelling and transcription via negatively regulating a chromatin remodeler Brahma.https://doi.org/10.1038/ncomms12988
spellingShingle Sung-Tae Hong
Kwang-Wook Choi
Antagonistic roles of Drosophila Tctp and Brahma in chromatin remodelling and stabilizing repeated sequences
Nature Communications
title Antagonistic roles of Drosophila Tctp and Brahma in chromatin remodelling and stabilizing repeated sequences
title_full Antagonistic roles of Drosophila Tctp and Brahma in chromatin remodelling and stabilizing repeated sequences
title_fullStr Antagonistic roles of Drosophila Tctp and Brahma in chromatin remodelling and stabilizing repeated sequences
title_full_unstemmed Antagonistic roles of Drosophila Tctp and Brahma in chromatin remodelling and stabilizing repeated sequences
title_short Antagonistic roles of Drosophila Tctp and Brahma in chromatin remodelling and stabilizing repeated sequences
title_sort antagonistic roles of drosophila tctp and brahma in chromatin remodelling and stabilizing repeated sequences
url https://doi.org/10.1038/ncomms12988
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AT kwangwookchoi antagonisticrolesofdrosophilatctpandbrahmainchromatinremodellingandstabilizingrepeatedsequences