Protective effect of 3-n-butylphthalide against intrastriatal injection of malonic acid-induced neurotoxicity and biochemical alteration in rats

Protective effect of 3-n-butylphthalide against intrastriatal injection of malonic acid-induced neurotoxicity and biochemical alteration in rats

Mitochondrial abnormalities and a defective expression of neurotrophic factors contribute to neuronal damage in Huntington's disease (HD). HD patients showed a reduction in transforming growth factor-β1 (TGF-β1) levels in the peripheral blood and in cortical neurons. 3-n-butylphthalide (NBP) is...

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Bibliographic Details
Main Authors:	Chunling Yuan, Li Zheng, Yingdai Zhao
Format:	Article
Language:	English
Published:	Elsevier 2022-11-01
Series:	Biomedicine & Pharmacotherapy
Subjects:	3-n-Butylphthalide Huntington's disease Malonic acid Mitochondria TGF-β1
Online Access:	http://www.sciencedirect.com/science/article/pii/S0753332222010538

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