Transcriptional Suppression of the NLRP3 Inflammasome and Cytokine Release in Primary Macrophages by Low-Dose Anthracyclines
Tissue-resident macrophages play critical roles in controlling homeostasis, tissue repair, and immunity. Inflammatory macrophages can sustain tissue damage and promote the development of fibrosis during infections and sterile tissue injury. The NLRP3 inflammasome and its effector cytokine IL-1&#...
Main Authors: | Nilay Köse-Vogel, Sven Stengel, Elena Gardey, Tatiana Kirchberger-Tolstik, Philipp A. Reuken, Andreas Stallmach, Tony Bruns |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-12-01
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Series: | Cells |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4409/9/1/79 |
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