Advanced Invasive Extramammary Paget’s Disease Concomitant with Cecal Cancer Possessing Rare Variant of TP53 Single Nucleotide Polymorphism

Advanced Invasive Extramammary Paget’s Disease Concomitant with Cecal Cancer Possessing Rare Variant of TP53 Single Nucleotide Polymorphism

Patients with invasive extramammary Paget’s disease have an increased risk of secondary malignancy, mostly occurring colorectal carcinoma. TP53 is a regulator of apoptosis, cell cycle arrest, and DNA damage response pathways, and has been reported as one of the genetic biomarkers for colorectal carc...

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Bibliographic Details
Main Authors: Yumi Kambayashi, Taku Fujimura, Kentaro Ohuchi, Hisayuki Tono, Yoshihiro Ishida, Atsushi Otsuka, Setsuya Aiba
Format: Article
Language:English
Published: Karger Publishers 2019-11-01
Series:Case Reports in Oncology
Subjects:
cecal carcinoma
empd
tp53 snp
immunohistochemical staining
ck7
ck20
Online Access:https://www.karger.com/Article/FullText/504339

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