Questionnaire-based computational screening of adult ADHD

Abstract Background ADHD is classically seen as a childhood disease, although it persists in one out of two cases in adults. The diagnosis is based on a long and multidisciplinary process, involving different health professionals, leading to an under-diagnosis of adult ADHD individuals. We therefore...

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Main Authors: Arthur Trognon, Manon Richard
Format: Article
Language:English
Published: BMC 2022-06-01
Series:BMC Psychiatry
Subjects:
Online Access:https://doi.org/10.1186/s12888-022-04048-1
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author Arthur Trognon
Manon Richard
author_facet Arthur Trognon
Manon Richard
author_sort Arthur Trognon
collection DOAJ
description Abstract Background ADHD is classically seen as a childhood disease, although it persists in one out of two cases in adults. The diagnosis is based on a long and multidisciplinary process, involving different health professionals, leading to an under-diagnosis of adult ADHD individuals. We therefore present a psychometric screening scale for the identification of adult ADHD which could be used both in clinical and experimental settings. Method We designed the scale from the DSM-5 and administered it to n = 110 control individuals and n = 110 ADHD individuals. The number of items was reduced using multiple regression procedures. We then performed factorial analyses and a machine learning assessment of the predictive power of the scale in comparison with other clinical scales measuring common ADHD comorbidities. Results Internal consistency coefficients were calculated satisfactorily for TRAQ10, with Cronbach’s alpha measured at .9. The 2-factor model tested was confirmed, a high correlation between the items and their belonging factor. Finally, a machine-learning analysis showed that classification algorithms could identify subjects’ group membership with high accuracy, statistically superior to the performances obtained using comorbidity scales. Conclusions The scale showed sufficient performance for its use in clinical and experimental settings for hypothesis testing or screening purpose, although its generalizability is limited by the age and gender biases present in the data analyzed.
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spelling doaj.art-51b5318462694bc283356123b03c2ac22022-12-22T00:28:01ZengBMCBMC Psychiatry1471-244X2022-06-012211810.1186/s12888-022-04048-1Questionnaire-based computational screening of adult ADHDArthur Trognon0Manon Richard1ClinicogClinicogAbstract Background ADHD is classically seen as a childhood disease, although it persists in one out of two cases in adults. The diagnosis is based on a long and multidisciplinary process, involving different health professionals, leading to an under-diagnosis of adult ADHD individuals. We therefore present a psychometric screening scale for the identification of adult ADHD which could be used both in clinical and experimental settings. Method We designed the scale from the DSM-5 and administered it to n = 110 control individuals and n = 110 ADHD individuals. The number of items was reduced using multiple regression procedures. We then performed factorial analyses and a machine learning assessment of the predictive power of the scale in comparison with other clinical scales measuring common ADHD comorbidities. Results Internal consistency coefficients were calculated satisfactorily for TRAQ10, with Cronbach’s alpha measured at .9. The 2-factor model tested was confirmed, a high correlation between the items and their belonging factor. Finally, a machine-learning analysis showed that classification algorithms could identify subjects’ group membership with high accuracy, statistically superior to the performances obtained using comorbidity scales. Conclusions The scale showed sufficient performance for its use in clinical and experimental settings for hypothesis testing or screening purpose, although its generalizability is limited by the age and gender biases present in the data analyzed.https://doi.org/10.1186/s12888-022-04048-1ADHDDiagnosisMachine-learningClinical scalePsychometrics - adult
spellingShingle Arthur Trognon
Manon Richard
Questionnaire-based computational screening of adult ADHD
BMC Psychiatry
ADHD
Diagnosis
Machine-learning
Clinical scale
Psychometrics - adult
title Questionnaire-based computational screening of adult ADHD
title_full Questionnaire-based computational screening of adult ADHD
title_fullStr Questionnaire-based computational screening of adult ADHD
title_full_unstemmed Questionnaire-based computational screening of adult ADHD
title_short Questionnaire-based computational screening of adult ADHD
title_sort questionnaire based computational screening of adult adhd
topic ADHD
Diagnosis
Machine-learning
Clinical scale
Psychometrics - adult
url https://doi.org/10.1186/s12888-022-04048-1
work_keys_str_mv AT arthurtrognon questionnairebasedcomputationalscreeningofadultadhd
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