Immune characterization of breast cancer metastases: prognostic implications

Immune characterization of breast cancer metastases: prognostic implications

Abstract Background Tumor-infiltrating lymphocytes (TILs) evaluated in primary breast cancer (BC) convey prognostic information. Limited data in the metastatic setting are available. Methods Secondary lesions from 94 BC patients, 43 triple-negative (TN) and 51 HER2-positive, were evaluated for TILs...

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Main Authors: Maria Vittoria Dieci, Vassilena Tsvetkova, Enrico Orvieto, Federico Piacentini, Guido Ficarra, Gaia Griguolo, Federica Miglietta, Tommaso Giarratano, Claudia Omarini, Serena Bonaguro, Rocco Cappellesso, Camillo Aliberti, Grazia Vernaci, Carlo Alberto Giorgi, Giovanni Faggioni, Giulia Tasca, Pierfranco Conte, Valentina Guarneri
Format: Article
Language:English
Published: BMC 2018-06-01
Series:Breast Cancer Research
Subjects:
Metastatic breast cancer
Tumor-infiltrating lymphocytes
PD-L1
Triple negative
HER2
Online Access:http://link.springer.com/article/10.1186/s13058-018-1003-1

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