Fat infiltration in the thigh muscles is associated with symptomatic spinal stenosis and reduced physical functioning in adults with achondroplasia

Fat infiltration in the thigh muscles is associated with symptomatic spinal stenosis and reduced physical functioning in adults with achondroplasia

Abstract Background Symptomatic spinal stenosis is a prevalent complication in adults with achondroplasia. Increased muscle fat infiltration (MFI) and reduced thigh muscle volumes have also been reported, but the pathophysiology is poorly understood. We explored whether the increased MFI and reduced...

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Bibliográfalaš dieđut
Váldodahkkit: Svein O. Fredwall, Jennifer Linge, Olga de Vries, Olof Dahlqvist Leinhard, Heidi Beate Eggesbø, Harald Weedon-Fekjær, Mikael Petersson, Per Widholm, Grethe Månum, Ravi Savarirayan
Materiálatiipa: Artihkal
Giella:English
Almmustuhtton: BMC 2023-02-01
Ráidu:Orphanet Journal of Rare Diseases
Fáttát:
Achondroplasia
Body composition
Intramuscular fat
Magnetic resonance imaging
Muscle fat infiltration
Rehabilitation
Liŋkkat:https://doi.org/10.1186/s13023-023-02641-5

Interneahtta

https://doi.org/10.1186/s13023-023-02641-5

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