Risk of teenage pregnancy among adolescents with borderline personality disorder: A nationwide longitudinal study
Background: Evidence suggested that borderline personality disorder (BPD) is related to the increased likelihood of risky sexual behaviors and that BPD is one of the most important risk factors of teenage pregnancy among adolescents. But whether adolescent BPD is independently associated with teenag...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2021-01-01
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| Series: | Taiwanese Journal of Psychiatry |
| Subjects: | |
| Online Access: | http://www.e-tjp.org/article.asp?issn=1028-3684;year=2021;volume=35;issue=1;spage=26;epage=31;aulast=Chen |
| _version_ | 1818730967365320704 |
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| author | Mu- Hong Chen Shih- Jen Tsai |
| author_facet | Mu- Hong Chen Shih- Jen Tsai |
| author_sort | Mu- Hong Chen |
| collection | DOAJ |
| description | Background: Evidence suggested that borderline personality disorder (BPD) is related to the increased likelihood of risky sexual behaviors and that BPD is one of the most important risk factors of teenage pregnancy among adolescents. But whether adolescent BPD is independently associated with teenage pregnancy remains uncertain. Methods: We enrolled 809 adolescent girls with BPD and 8,090 without BPD between 2001 and 2009 and followed them up to the end of 2011 for the identifying any teenage pregnancy and repeated teenage pregnancy. Comorbidities of depressive disorder, bipolar disorder, as well as alcohol and substance use disorder were assessed. Psychotropic medications including antidepressants, mood stabilizers, and second-generation (atypical) antipsychotics were also identified. Results: Using Cox regression analyses with an adjustment of demographic characteristics, psychiatric comorbidities, and psychotropic medications showed that adolescents with BPD had significant increased risks of any teenage pregnancy (hazard ratio [HR] = 14.53, 95% confidence interval [CI] = 9.89–21.37, p < 0.05), and repeated teenage pregnancy (HR = 30.43, 95% CI = 17.32–53.45, p < 0.05) during the follow-up compared with non-BPD controls. Psychotropic medications were not significantly associated with the risks of any teenage pregnancy and repeated teenage pregnancy. Discussion: Adolescent BPD was an independent risk factor of any teenage pregnancy and repeated teenage pregnancy, regardless of the comorbidities of alcohol and substance use disorders. Whether the prompt intervention toward adolescent BPD may reduce the risks of any teenage pregnancy and repeated teenage pregnancy would need further investigation. |
| first_indexed | 2024-12-17T23:10:12Z |
| format | Article |
| id | doaj.art-51c0f74060214057a5fffd4cb959c9ee |
| institution | Directory Open Access Journal |
| issn | 1028-3684 2666-2078 |
| language | English |
| last_indexed | 2024-12-17T23:10:12Z |
| publishDate | 2021-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Taiwanese Journal of Psychiatry |
| spelling | doaj.art-51c0f74060214057a5fffd4cb959c9ee2022-12-21T21:29:09ZengWolters Kluwer Medknow PublicationsTaiwanese Journal of Psychiatry1028-36842666-20782021-01-01351263110.4103/TPSY.TPSY_6_21Risk of teenage pregnancy among adolescents with borderline personality disorder: A nationwide longitudinal studyMu- Hong ChenShih- Jen TsaiBackground: Evidence suggested that borderline personality disorder (BPD) is related to the increased likelihood of risky sexual behaviors and that BPD is one of the most important risk factors of teenage pregnancy among adolescents. But whether adolescent BPD is independently associated with teenage pregnancy remains uncertain. Methods: We enrolled 809 adolescent girls with BPD and 8,090 without BPD between 2001 and 2009 and followed them up to the end of 2011 for the identifying any teenage pregnancy and repeated teenage pregnancy. Comorbidities of depressive disorder, bipolar disorder, as well as alcohol and substance use disorder were assessed. Psychotropic medications including antidepressants, mood stabilizers, and second-generation (atypical) antipsychotics were also identified. Results: Using Cox regression analyses with an adjustment of demographic characteristics, psychiatric comorbidities, and psychotropic medications showed that adolescents with BPD had significant increased risks of any teenage pregnancy (hazard ratio [HR] = 14.53, 95% confidence interval [CI] = 9.89–21.37, p < 0.05), and repeated teenage pregnancy (HR = 30.43, 95% CI = 17.32–53.45, p < 0.05) during the follow-up compared with non-BPD controls. Psychotropic medications were not significantly associated with the risks of any teenage pregnancy and repeated teenage pregnancy. Discussion: Adolescent BPD was an independent risk factor of any teenage pregnancy and repeated teenage pregnancy, regardless of the comorbidities of alcohol and substance use disorders. Whether the prompt intervention toward adolescent BPD may reduce the risks of any teenage pregnancy and repeated teenage pregnancy would need further investigation.http://www.e-tjp.org/article.asp?issn=1028-3684;year=2021;volume=35;issue=1;spage=26;epage=31;aulast=Chenadolescentsborderline personality disorderearly pregnancyteenage pregnancy |
| spellingShingle | Mu- Hong Chen Shih- Jen Tsai Risk of teenage pregnancy among adolescents with borderline personality disorder: A nationwide longitudinal study Taiwanese Journal of Psychiatry adolescents borderline personality disorder early pregnancy teenage pregnancy |
| title | Risk of teenage pregnancy among adolescents with borderline personality disorder: A nationwide longitudinal study |
| title_full | Risk of teenage pregnancy among adolescents with borderline personality disorder: A nationwide longitudinal study |
| title_fullStr | Risk of teenage pregnancy among adolescents with borderline personality disorder: A nationwide longitudinal study |
| title_full_unstemmed | Risk of teenage pregnancy among adolescents with borderline personality disorder: A nationwide longitudinal study |
| title_short | Risk of teenage pregnancy among adolescents with borderline personality disorder: A nationwide longitudinal study |
| title_sort | risk of teenage pregnancy among adolescents with borderline personality disorder a nationwide longitudinal study |
| topic | adolescents borderline personality disorder early pregnancy teenage pregnancy |
| url | http://www.e-tjp.org/article.asp?issn=1028-3684;year=2021;volume=35;issue=1;spage=26;epage=31;aulast=Chen |
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